نتایج جستجو برای: urocortin

تعداد نتایج: 684  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Yael Kuperman Orna Issler Limor Regev Ifat Musseri Inbal Navon Adi Neufeld-Cohen Shosh Gil Alon Chen

In response to physiological or psychological challenges, the brain activates behavioral and neuroendocrine systems linked to both metabolic and emotional outputs designed to adapt to the demand. However, dysregulation of integration of these physiological responses to challenge can have severe psychological and physiological consequences, and inappropriate regulation, disproportional intensity...

2000
Gennady N. Smagin Stephen C. Heinrichs Adrian J. Dunn

Corticotropin-releasing hormone (CRH) and urocortin in the central nervous system affect behavior and can enhance behavioral responses to stressors. The action of CRH-related peptides is mediated through multiple receptors that differ markedly in their pharmacological profiles and anatomical distribution. Comparative pharmacology of CRH receptor agonists suggests that CRH, urocortin, sauvagine ...

Journal: :Trends in endocrinology and metabolism: TEM 2008
Yael Kuperman Alon Chen

The effects of stress on energy balance and the involvement of the neuropeptide corticotropin releasing factor in modulating the anorexia of stress and sympathetic nervous system tone are well recognized. Currently, studies centered on the roles of the more recently described members of this family of ligands, the urocortins, and their preferred receptor, the corticotropin releasing factor type...

Journal: :The Journal of clinical investigation 2006
Philip E Cryer

A reduced sympathoadrenal response, induced by recent antecedent hypoglycemia, is the key feature of hypoglycemia-associated autonomic failure (HAAF) and, thus, the pathogenesis of iatrogenic hypoglycemia in diabetes. Understanding of the mechanism(s) of that reduced response awaits new insight into its basic molecular, cellular, organ, and whole-body physiology and pathophysiology in experimen...

Journal: :Journal of Molecular Endocrinology 2010

Journal: :The Journal of Clinical Endocrinology & Metabolism 2004

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