BACKGROUND In many countries, 1 to 3% of newborn infants are conceived by assisted reproductive techniques (ART). Despite the success of ART, there is concern about the risk of congenital malformations among these infants. We report our experience to determine whether use of ART is associated with an increase in major congenital malformations or adverse pregnancy outcomes. MATERIALS AND METHO...

mycoplasmas hominis, mycoplasmas genitalium and ureaplasma urealyticum are associated with infections of the genitourinary tract, reproductive failure, and neonatal morbidity and mortality. a multiplex pcr was developed for simultaneously detection of these mycoplasmas species in a single amplification reaction. the total number of 104 samples was collected from 104 women’s genital specimens wi...

OBJECTIVES To report 2 cases of penile duplication and review the literature in an attempt to categorize the associated anomalies in relation to the degree of penile duplication. Embryologic considerations of this rare anomaly are also reviewed. METHODS We report 2 distinct cases of diphallia. In the first case, true complete penile duplication was associated with multiple malformations, incl...

Background: In the past 22 years, intracytoplasmic sperm injection (ICSI) on human oocytes become a successful method of treatment for most categories of infertility. But there are real concerns that possible malformations among ICSI infants are still not fully recognized. Despite the success of ICSI, the risk of major birth defects due to various parental factors or treatment may increase. We ...

INTRODUCTION In males the ectopic ureter usually drains into the prostate (50%). During ureteric developement a thin membrane (Chawalla's membrane) separates the lumen of the ureter and the urogenital sinus at the point where the ureter joins the urogenital sinus. This membrane ruptures allowing urin to drain from the ureter to the urogenital sinus. The authors reported a case of renal dysplasi...

Metanephric kidney induction critically depends on mesenchymal-epithelial interactions in the caudal region of the nephric (or Wolffian) duct. Central to this process, GDNF secreted from the metanephric mesenchyme induces ureter budding by activating the Ret receptor expressed in the nephric duct epithelium. A failure to regulate this pathway is believed to be responsible for a large proportion...

Sirenomelia, also known as "mermaid malformation/syndrome," is a rare, serious congenital anomaly characterized by variable degrees of fusion of the lower limbs and associated with severe malformations of vertebral, genitourinary, cardiovascular system and single umbilical artery. The first pregnancy of a 25-year-old woman resulted in one twin born by Cesarian section at 32 weeks' gestation, wh...

Introduction: Hypotrophy is a public health problem in developing countries. Its etiology multifactorial and it may be associated with high morbidity mortality. The objective of this study was to describe the epidemiological, clinical evolutionary profile hypotrophic newborns at term. Methodology: prospective, descriptive analytical conducted neonatology department MCUH N'Djamena from 01/06/201...