invasive meningococcal disease (imd) is a severe bacterial infectious disease with high mortality and morbidity rates worldwide. in recent years, industrialised countries have implemented vaccines targeting imd in their national immunisation programmes (nips). in 2002, the netherlands successfully implemented a single dose of meningococcal serogroup c conjugate vaccine at the age of 14 months a...

BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic has been going on for more than 2 years, with various treatments and diagnostic methods available. One of the most prized structures, receptor-binding domain (RBD) spike protein in severe acute respiratory syndrome coronavirus long thoroughly researched its function becoming target treatments, including a vaccine. The spike-RBD (sRBD) ant...

BACKGROUND. The COVID-19 vaccines currently in use require 2 doses to achieve optimal protection. Currently, there is no indication as whether individuals who have been exposed SARS-CoV-2 should be vaccinated, or they receive 1 vaccine doses.

Abstract The Susceptible-Isolated-Infected-Recovered-Vaccinated ( SI q IRV ) deterministic model is examined in this paper. This considers a nonlinear force of quarantine, infection and care, where vaccinated individuals lose their immunity after period time become susceptible to infection. Isolation the main key bringforth S I model. fundamentals reproduction number calculated using an outbrea...

Background: A COVID 19 vaccine is a intended to provide acquired immunity against severe acute respiratory syndrome corona virus 2. Ad26.COV2.S (Johnson & Johnson) adenovirus vector-based that targets the spike protein of SARS-CoV-2 virus, when it enters body stimulates immune response. Materials and methods: This was cross sectional study, health facility base, Conducted in Vacci...