نتایج جستجو برای: vaccine production
تعداد نتایج: 705105 فیلتر نتایج به سال:
Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the need for an improved global response in terms of shortening the time required to manufacture the vaccine and increasing production capacity. Here we describe the pre-clinical assessment of a novel 2009 H1N1 pandemic influenza vaccine based o...
tetanus is a disease caused by tetanus toxin, a potent inhibitor for the release of inhibitory neurotransmitter in the central nervous system that causes spastic paralysis. fragment c (52 kd) of this toxin is responsible for binding to the neuronal membrane. for this reason, and also its non toxigenic and immunogenic nature, this fragment might be ideal for new vaccine development. presently, w...
stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. these studies used to determine vaccine expiry date and vaccine efficacy. accelerated stability and long term stability study performed for three batches of trivalent oral poliomyelitis vaccine (opv) and three batches of monovalent opv (type1) manufactured by razi institute. after samplin...
Introduction: Inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary. The use of cell culture-based vaccine production is one way of overcoming the limitations of the egg-based method and securing a more rapid re...
The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine, testing of the safety and efficacy of the use of inactivated antigen plus adjuvant is needed. Here, we assessed various types of adjuvants in eyedrop as an anti-influenza serum and mucosal Ab production-enhancer in BALB/c mice. Among the ...
Ontology is a requirement engineering product and the key to knowledge discovery. It includes the terminology to describe a set of facts, assumptions, and relations with which the detailed meanings of vocabularies among communities can be determined. This is a qualitative content analysis research. This study has made use of ontology for the first time to discover the knowledge of vaccine in Ir...
The Epidemiology of poliomgelitis has been investigated in our country Pasteur Institute; the incidence of Poliomgelitis, after the age of 4 years i's rare, in Iran. Passive antibody of maternal origin do not interfere with production of active antibody after immunization. Inactivated Polio Vaccine (salk) has been effective in reducing the incidence of poliomgelitis by approximately 90 per ...
Introduction: Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of livestock that is categorized in list A of animal diseases by the World Organisation for Animal Health (OIE). Vaccination is effective against FMD and the vaccine production centers largely use the industrial ultra-filtration and chromatography in order to remove the cellular proteins...
introduction: inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary. the use of cell culture-based vaccine production is one way of overcoming the limitations of the egg-based method and securing a more rapid re...
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