Dystroglycan (Dg) is a transmembrane receptor for laminin that must be expressed at the right time and place in order to be involved in notochord morphogenesis. The function of Dg was examined in Xenopus laevisembryosby knockdownofDgandoverexpressionand replacement of the endogenousDgwith amutated form of the protein. This analysis revealed thatDg is required for correct laminin assembly, for c...
