BACKGROUND To identify an effective misoprostol-only regimen for the termination of second trimester pregnancy, we compared sublingual and vaginal administration of multiple doses of misoprostol in a randomized, placebo-controlled equivalence trial. METHODS Six hundred and eighty-one healthy pregnant women requesting medical abortion at 13-20 weeks' gestation were randomly assigned within 11 ...

CONTEXT Misoprostol, a synthetic E1 methyl analog prostaglandin, is at present receiving attention as a cervical modifier and labor induction agent. However, there is still a need for better determination of its safety and effectiveness. OBJECTIVE To compare intravaginal misoprostol versus intravenous oxytocin for cervical ripening and labor induction in pregnant women with unripe cervices. ...

background: misoprostol, a prostaglandin e1 analogue compared to prostaglandin e2, has the advantage of being inexpensive and stable at room temperature, with its proven efficacy and safety. however studies on the effect of ph on the efficacy of misoprostol have yielded conflicting results. thus its use in the induction of labour in patients with premature rupture of membrane requires further i...

BACKGROUND Intrauterine insemination (IUI) is one of the most appropriate and cost-effective methods in infertility treatment. OBJECTIVE We aimed to investigate effect of vaginal misoprostol on pregnancy rate after IUI. MATERIALS AND METHODS Two hundred and ten infertile women who were referred to Infertility Clinic of Alzahra Hospital by an indication of IUI during 2012-2013 were randomly ...

BACKGROUND & OBJECTIVE Medical abortion though legalized in India, is still not very popular. A disadvantage of medical abortion is the longer duration of bleeding compared with surgical abortion which may reduce acceptability. Due consideration needs to be given to the issues related to medical abortion for improving the reproductive health status of women suffering from consequences of unsafe...

Induction of labour is a common need in obstetrics ward. There are various complications and drug side effects associated with it. This study has been designed to compare the safety and efficacy of 50μg intra-vaginal misoprostol (PGE1 analogue)with 0.5mg intracervical dinoprostone gel (PGE2). . 40 pregnant women with different indications of induction of labour participated in the study. They w...

AIM To compare the efficacy and safety of two misoprostol dosing regimens for induction of labour in primiparous (1P) and multiparous (>1P) women. METHODS Retrospective study of induction of labour using vaginal misoprostol 25 μg vs. 50 μg every 6 h in 942 women at a tertiary centre. The main outcome variables are induction-to-delivery interval, latency period duration, vaginal delivery withi...

Objective: To compare the efficacy and safety of oral misoprostol with prostaglandin E2 vaginal tablets for ripening of cervix and induction of labour at term. Study Design: A non blinded, randomised, controlled trial. Place and Duration of Study: Department of Obstetrics and Gynaecology, Pakistan Air Force Hospital, Air Headquarters Islamabad from July 2005 to January 2006. Patients and Method...

Background and objective: The objective of this work is to match the security effectiveness two treatment modalities (Misoprostol versus Letrozol with Misoprostol) in medical 1st trimesteric missed miscarriages. Methods: This an interventional randomized case-control investigation that was performed at outpatient antenatal care clinic Luxor General Hospital during period from February December ...

Objectives: To compare the efficacy and safety of 25 mcg intravaginal misoprostol vs 50 mcg misoprostol for induction of labor. Material and methods: This study group consisted of 100 cases of low-risk singleton pregnancies attending the antenatal clinic of SAH and RC, or admitted to the antenatal ward. Study group included singleton pregnancy, Over 37 weeks of gestation with Vertex presentatio...