E-health, enabled by ubiquitous computing and communication technologies, is facilitating a fundamental shift in the age old praxis of healthcare. It is revolutionizing healthcare in the 21 century in much the same way as the arrival of modern medicine and vaccines did in the 19 century. E-health lies at the intersection of diverse disciplines including healthcare, computer science, information...

Concurrent engineering initiatives and the closely related principle of front-loading development processes identifying and solving problems early rather than waiting for traditional development and test processes to uncover them have been shown to be highly effective in improving product development performance. This often means shifting to new experimentation technologies that can be used muc...

As exclusively technology-focused solutions do not provide any strategic competitive advantages nowadays ([1]), IT service provision needs to focus on business requirements. Consequently, adequately aligned IT services need to combine a good efficiency-/effectiveness ratio and adequate innovation power with regard to a business’ overall strategic objectives ([2]). According to Henderson and Ven...

It is diffi cult to argue against the clinical usefulness of endobronchial ultrasound (EBUS). Moreover, the benefi ts of EBUS extend beyond the clinical scope of the patient, lowering the cost burden on the health-care system. 1 However, the analysis by Pastis et al 2 in an issue of CHEST (February 2012) of its financial impact leaves much to be desired in offering a realistic assessment. Marke...

one of the most controversial problems in western epistemology is the division of propositions into analytic and synthetic. this division drew the attention of many proponents and opponents and faced many objections. one the most important objections which if valid enough, can destroy the basis of this division and resulting epistemological consequences is the of relativity of both analytic as ...