the most important progress in the field of retinal diseases during recent years might be the introduction of pharmacotherapy. age-related macular degeneration for instance was an irreversible disease leading to permanent anatomical and functional changes in the macula up to the previous decade; however, the use of anti-vascular endothelial growth factor agents (anti-vegfs) not only stops the p...

Abstract Vascular inflammation activated by pro-inflammatory cytokines is an inflammatory response that occurs in the early stages of atherosclerosis. Endothelial dysfunction vascular begins with expression cell surface adhesion molecules cytokines. The purpose this study was to evaluate and verify effects isobavachalcone. In study, we investigated isobavachalcone on responses induced tumor nec...

New blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ECs) which in turn give rise to primitive capillary network. Human cord blood (HCB) contains large subsets of mononuclear cells (MNCs) that can be differentiated into endothelial-like cells in vitro. Human mononuclear progenitor cells were purified from fresh umb...

Regenerative Vascular Tissue Engineering In article number 2200050, Quinton Smith and co-workers review strategies for regenerative vascular tissue engineering. The vasculature is a conduit that links various organ systems, guiding development, homeostasis, regeneration. They reflect in this cover the ability of cells (green endothelial cells) to self-assemble interact with parenchymal (red, st...

background: vascular endothelial growth factor (vegf) has a key role in angiogene-sis and in transplantation. the level of vegf is related to the differences in the dna sequence of its promoter region. objectives: in this study, the association between the combination of vegf –1154 g and –2578 c alleles and vegf production by lps-stimulated pbmcs was investigated. in addition; the relationship ...

Background: New blood vessels formation is a critical step in tumor progression. Vascular density affects the clinical outcome and prognosis of malignant tumors. The aim of this study was to investigate the relation between the Vascular Endothelial Growth Factor (VEGF) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (OSCC). &nbsp...

Leaf Veins The leaf vein is the “vascular system” in plants. In article 2201220 by Kelvin W. K. Yeung, Xin Zhao, and co-workers, a leaf-vein micropattern engraved on PGLADMA polymer membrane, serving as “running tracks” for vascular endothelial cells to facilitate hierarchical functional reconstruction. membrane can induce cell differentiation, vasculature reconstruction, vessel maturation.

Objective: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in contrast, some suggested that direct cytotoxicity has role in endothelial cell disturbances. This study was to evaluate the...