OBJECTIVES To evaluate the diagnostic value of plasma protein levels for pulmonary vascular permeability and acute respiratory distress syndrome. During acute lung injury and acute respiratory distress syndrome, increased vascular permeability induces protein-rich fluid extravasation. We hypothesized that plasma protein levels predict increased vascular permeability and acute respiratory distre...

Letter by Bhupali and Labovitz Regarding Article, “Clinical Scores for Predicting Recurrence After Transient Ischemic Attack or Stroke: How Good Are They?” To the Editor: Lemmens et al were unable to validate several prediction models of stroke recurrence after transient ischemic attack (TIA) or minor stroke and suggest that methodological differences between studies explain the variation. Howe...

BACKGROUND The purpose of the present study was to assess the influence of vascular factors on the degree of intensity and rate of progression of cognitive disorders in the course of Alzheimer Disease (AD). MATERIAL AND METHODS The research group consisted of 39 persons, all of whom were diagnosed with AD according to the NINCDS/ADRDA criteria. We divided these patients into 2 subgroups, base...

BACKGROUND AND PURPOSE BOLD MR imaging combined with a technique for precision control of end-tidal pCO(2) was used to produce quantitative maps of CVR in patients with Moyamoya disease. The technique was validated against measures of disease severity by using conventional angiography; it then was used to study the relationship between CVR, vascular steal, and disease severity. MATERIALS AND ...

BACKGROUND/AIMS The purpose of our study was to evaluate vascular risk factors and other clinical variables as predictors of cognitive and functional decline in elderly patients with mild to moderate dementia. METHODS The clinical characteristics of 82 elderly patients (mean age 79.0 ± 5.9 years; 67.1% females) with mild to moderate dementia were obtained at baseline, including years of educa...