BACKGROUND Rhodiola rosea (R. rosea) is grown at high altitudes and northern latitudes. Due to its purported adaptogenic properties, it has been studied for its performance-enhancing capabilities in healthy populations and its therapeutic properties in a number of clinical populations. To systematically review evidence of efficacy and safety of R. rosea for physical and mental fatigue. METHOD...

BACKGROUND Rhodiola rosea (R. rosea) is a botanical adaptogen with putative anti-stress and antidepressant properties. Evidence-based data supporting the effectiveness of R. rosea for depression in adults is limited, and therefore a comprehensive review of available animal and human studies suggesting a putative antidepressant action is warranted. PURPOSE A review of the literature was undert...

BACKGROUND Rhodiola rosea (golden root) is a unique phytoadaptagen with immunomodulatory, antioxidant, anti-inflammatory and antinociceptive activity. AIM The aim of this study was to evaluate the antinociceptive and anti-inflammatory effects of the alcohol/water extract of Rhodiola rosea roots in rats. MATERIALS AND METHODS Thirty male Wistar rats were used in the study. They were divided ...

The purpose of this study was to investigate the effects of Rhodiola rosea extract and depression on the serotonin (5-HT) level, cell proliferation and quantity of neurons at cerebral hippocampus of depressive rats induced by Chronic Mild Stress (CMS). Seventy male Sprague-Dawley rats were divided into seven groups (10 per group): normal control group, untreated depressive rat model group, nega...

Concentration-dependent effects of aqueous extract from R. rosea root on long-term survival and stress resistance of budding yeast Saccharomyces cerevisiae were studied. At low concentrations, R. rosea aqueous extract extended yeast chronological lifespan, enhanced oxidative stress resistance of stationary-phase cells and resistance to number stressors in exponentially growing cultures. At high...

Rhodiola rosea is a perennial plant at high altitudes in the Arctic and mountainous regions throughout Europe and Asia. It contains various active compounds e.g. phenylpropanoids, phenylethanol derivatives, flavanoids, monoterpenes, triterpenes, phenolic acids, and essential oils. Salidroside and tyrosol are the major bioactive constituents in Rhodiola rosea. Traditionally, Rhodiola rosea is us...

BACKGROUND Rhodiola rosea is an herbal supplement that many in the general population in Russia and elsewhere in the world have used for decades to alleviate everyday anxiety, depression, and insomnia. Whether R. rosea is effective in reducing similar symptoms in clinical samples is unknown. The goal of this pilot study was to evaluate whether R. rosea is effective in reducing symptoms of gener...

INTRODUCTION Pityriasis rosea is a self-limited inflammatory condition of the skin that mostly affects healthy children and adolescents. Atypical cases of Pityriasis rosea are fairly common and less readily recognized than typical eruptions, and may pose a diagnostic challenge. CASE PRESENTATION We report the case of a 12-year-old black child that developed an intense pruritic papular eruptio...

Electrophoresis of proteins, especially seed proteins, and karyological studies are useful techniques for determining species and solving the problems of modern taxonomy. The present study was carried out on two species of the Apocynaceae family, Rhazya stricta Decasine and Nerium 01eancder.L. Seed samples of these two genera were taken from the south-east of Iran and SDS-PAGE analysis of th...