AIMS To evaluate the effectiveness of core vitrectomy preceding triple corneal procedure (penetrating keratoplasty, extracapsular cataract extraction, and intraocular lens (IOL) implantation). METHODS Thirty one consecutive eyes of 31 patients with indication for triple corneal procedure were randomly assigned to either triple procedure with core vitrectomy (vitrectomy group) or without vitre...

PURPOSE To determine whether supervision by an attending who is new to surgical teaching, or an experienced attending measurably influences intraoperative complications rates or outcomes in phacoemulsification performed by ophthalmology residents. SETTING Single tertiary hospital. DESIGN Retrospective cohort study. METHODS Resident-performed phacoemulsification cases supervised by one nov...

Vitreous floaters are one of the most common complain ophthalmological patients. The aetiology includes pathological process (vitreous haemorrhages, injuries, diabetics or uveitis) and also natural age-related changes in vitreous body. Diagnosis treatment depends on severity symptoms. Process posterior detachment requires particularly careful monitoring, because potential complications such as ...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by post-transcriptional inhibition of mRNA translation. Dysregulation of miRNAs, including circulating miRNAs, has been reported to play an important role in the development of various diseases, including fibrotic diseases. Aberrant expression of miRNAs in the vitreous humor of vitreoretinal diseased eyes has been reporte...

The permeability of the blood-ocular barrier was investigated in five monkeys using vitreous fluorophotometry (VFP). Inward permeability (Pin) of the blood-retinal barrier was calculated by a computer simulation method. Kinetic VFP was performed after intravitreal injection of fluorescein (F) or fluorescein monoglucuronide (FG). The estimated mean value of Pin (x10(-6) cm/min) was 4.8 (SD 1.2)....

The eye is a well-suited organ for local delivery of therapeutics to treat vitreous inflammation as well as other pathologic conditions that induce visual loss. Several conditions are particularly challenging to treat and often require chronic courses of therapy. The use of implantable intravitreal devices for drug delivery is an emerging field in the treatment of vitreous inflammation as well ...

PURPOSE Vascular endothelial growth factor (VEGF) concentrations in various regions of the vitreous were examined in patients with diabetic macular edema (DME) to explore the possibility of a concentration gradient in the vitreous. METHODS Vitreous samples were collected during vitrectomy from 71 eyes of 71 patients with DME and without posterior vitreous detachment who had not undergone panr...

THE effect of hyaluronidase injections on the slit-lamp appearance and the composition of the vitreous humour of the rabbit has been examinfed. The purpose of the experiments has been to see whether disaggregation of hyaluronic acid from a viscous to a non-viscous form in the vitreous humour is a permanent change and whether any visible change persists as a result of hyaluronidase action. Very ...

In assessing a patient who has experienced an acute disturbance of vision in an uninflamed eye an accurate history is crucial, because it may be that a longstanding visual defect has only just been noticed by the patient. It is important to make this differentiation as this alters the range of diagnoses and the urgency of treatment. Acute visual disturbance ofunknown cause requires urgent refer...