This paper examines current concepts concerning "limiting" factors in human endurance performance by modeling marathon running times on the basis of various combinations of previously reported values of maximal O2 uptake (VO2max), lactate threshold, and running economy in elite distance runners. The current concept is that VO2max sets the upper limit for aerobic metabolism while the blood lacta...

INTRODUCTION The maximal oxygen uptake (VO2max) can be defined as the maximum integrated capacity of the pulmonary, cardiovascular and muscular systems to uptake, transport and utilize O2, respectively (Poole et al., 2008). Usually measured by the incremental exercise test in the treadmill or cycle ergometer, the VO2max test has become a cornerstone in clinical and applied physiology involving ...

Previous studies of the effect of age on maximal aerobic capacity (maximal rate of oxygen consumption, VO2max) in horses have only grouped horses (young, middle-aged and old) for statistical analysis. Those experiments were not designed to determine a break point due to age. The purpose of this study was to utilize data collected over the last 15 years to test the nature of the association betw...

The purpose of this study was to test the accuracy of the 20-m multi-stage shuttle run (SR) test to predict VO2max in young adults. VO2max was measured during a graded treadmill test in 60 men and 62 women (mean age 25.3 and 25.1 years, respectively). Each subject was familiarized with the SR procedure and the completed the SR test to predict VO2max on a separate day. The mean terminal SR stage...

BACKGROUND This study examined substrate oxidation at high-intensity exercise and aimed to determine when fat oxidation ends (FATmin). We hypothesized the existence of a connection between the anaerobic threshold (AnT) and FATmin point. METHODS Breath-by-breath data obtained from indirect calorimetry during a graded treadmill test were used to measure substrate oxidation and maximal oxygen up...

Objectives: In Finland, testing cardiorespiratory fitness (VO2max) is popular in health promotion programs and work ability evaluations. The most common instruments used for this purpose are the submaximal cycle ergometer test, and the 2-km walking test. However, limited data exist on the associations between VO2max and wellbeing in working age adults. The aim of the study was to evaluate how t...

Twenty-one women subjects were matched in terms of their Vo2max and assigned to one of two groups: (1) training at 30 s; or (2) 2 min with a 1:1 work: relief ratio (1:1 WR) before participating in a 7-week training programme which began at an intensity of 85% Vo2max and increased 5% every two weeks (90% and 95% Vo2max). The subjects trained to exhaustion four times per week. Maximal oxygen cons...

BACKGROUND There is emerging evidence that adjuvant treatments for breast cancer negatively impact cardiorespiratory fitness (CRF) or Vo2max, a key predictor of cardiovascular risk. Although a number of studies have measured CRF in breast cancer patients, there is currently limited data regarding expected CRF values in this patient population. Given that CRF is a poor prognostic sign and recent...

An animal model was developed to study effects on components of exercise physiology of both "nature" (10 generations of genetic selection for high voluntary activity on running wheels) and "nurture" (7-8 wk of access or no access to running wheels, beginning at weaning). At the end of the experiment, mice from both wheel-access groups were significantly lighter in body mass than mice from seden...

The influence of cardiorespiratory fitness (VO2max) on anthropometric variables and PPARG mRNA expression was investigated. Monozygotic twin pairs aged 11-18 years were grouped into discordant (D) and concordant (C) high and low VO2max groups. VO2max was determined by progressive maximal exercise test on treadmill with gas exchange analysis. Body mass (BM), BMI, waist circumference (WC), tricep...