Temperature-responsive microgels find widespread applications as soft materials for designing actuators in microfluidic systems, carriers drug delivery or catalysts, functional coatings, and adaptable sensors. The key property is their volume phase transition temperature, which allows thermally induced reversible swelling/deswelling. It determined by the gel's chemical structure well network to...

Monodispersed poly(N-isopropylacrylamide) (PNIPAM) nanoparticles, with hydrodynamic radius less than 50 nm at room temperature, have been synthesized in the presence of a large amount of emulsifiers. These microgel particles undergo a swollen–collapsed volume transition in an aqueous solution when the temperature is raised to around 34 °C. The volume transition and structure changes of the micr...

The antagonizing action of hydrostatic pressure against anesthesia is well known. The present study was undertaken to quantitate the effects of hydrostatic pressure and anesthetics upon the phase-transition temperature of dipalmitoyl phosphatidylcholine vesicles. The drugs used to anesthetize the phospholipid vesicles included an inhalation anesthetic, halothane, a dissociable local anesthetic,...

Thermo-dynamic volume phase transition mechanisms of poly[oligo(ethylene glycol)methacrylate] (POEGMA) based microgels with poly(ionic liquid) (PIL) cross-linking moieties are investigated in detail on the basis of temperature-dependent Fourier transform infrared (FTIR) spectroscopy. The original FTIR data are further analysed by two-dimensional correlation spectroscopy (2Dcos) with the perturb...

P, Vm, Tdata have been measured for the smectic, nematic and isotropic phases of 4'-n-octyl-biphenyl-4-carbonitrile (8CB) in the temperature range 300-370 K and pressures up to 300 MPa. At atmospheric pressure all phase transitions appear to be of first order due to a discontinuity in the density. The volume change at the smectic A nematic transition is only a tenth of the volume change at the ...

The small all-beta protein tendamistat folds and unfolds with two-state kinetics. We determined the volume changes associated with the folding process by performing kinetic and equilibrium measurements at variable pressure between 0.1 and 100 MPa (1 to 1, 000 bar). GdmCl-induced equilibrium unfolding transitions reveal that the volume of the native state is increased by 41.4 +/- 2.0 cm(3)/mol r...

Effect of the volume phase transition on the diffusion and concentration of molecular probes was studied in temperature-responsive polymeric hydrogels. Results were compared for two gels, poly(N-isopropylacrylamide), NIPA, and poly(N-isopropylacrylamide-co-acrylic acid), NIPA-AA. These gels undergo discontinuous, reversible volume phase transition as a response to temperature changes; this tran...