نتایج جستجو برای: vulnerability to addiction

تعداد نتایج: 10628262  

2015
Loren H Parsons

| Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such as palatable food, sexual activity and social interaction) and modulates the rewarding effects of addictive drugs. Pathological forms of natural and drug-induced reward are associated with dysregulated eCB signalling that may derive from pre-existing genetic factors or from prolonged drug exposure. Impa...

Journal: :Annual review of psychology 2008
George F Koob Michel Le Moal

A neurobiological model of the brain emotional systems has been proposed to explain the persistent changes in motivation that are associated with vulnerability to relapse in addiction, and this model may generalize to other psychopathology associated with dysregulated motivational systems. In this framework, addiction is conceptualized as a cycle of decreased function of brain reward systems an...

Journal: :تحقیقات علوم رفتاری 0
مجتبی حبیبی احمد عاشوری mojtaba habibi ahmad ashori

abstract aim and background: the aim of the study was to investigate the relationship of coping skills and mental health with attitude to addiction in high school students. method s and materials: the subjects of this study consisted of 600 high school students (300 girls, 300 boys) who were selected by multiphase cluster sampling from high schools in city of shiraz and were assessed with copin...

Journal: :Frontiers in bioscience 2018
Kenneth Blum Amanda L C Chen Panayotis K Thanos Marcelo Febo Zsolt Demetrovics Kristina Dushaj Abraham Kovoor David Baron David E Smith Alphonso Kenison Roy Lyle Fried Thomas J H Chen Edwin Chapman Edward J Modestino Bruce Steinberg Rajendra D Badgaiyan

The interaction of neurotransmitters and genes that control the release of dopamine is the Brain Reward Cascade (BRC). Variations within the BRC, whether genetic or epigenetic, may predispose individuals to addictive behaviors and altered pain tolerance. This discussion authored by a group of concerned scientists and clinicians examines the Genetic Addiction Risk Score (GARS), the first test to...

Journal: :Behavioral neuroscience 2007
R Andrews Chambers Tammy J Sajdyk Susan K Conroy Joan E Lafuze Stephanie D Fitz Anantha Shekhar

Neurodevelopmental abnormalities of temporal-limbic structures may underlie both adult psychiatric syndromes and increased addiction vulnerability, leading to high frequencies of "dual diagnosis" disorders. Although the amygdala is implicated in various mental disorders and drug addiction, no studies have explored the impact of early developmental damage to the amygdala on phenotypes relating t...

2009
Andrew J Lawrence Jason Luty Nadine A Bogdan Barbara J Sahakian Luke Clark

AIMS Problem gambling has been proposed to represent a 'behavioural addiction' that may provide key insights into vulnerability mechanisms underlying addiction in brains that are not affected by the damaging effects of drugs. Our aim was to investigate the neurocognitive profile of problem gambling in comparison with alcohol dependence. We reasoned that shared deficits across the two conditions...

Objective: This study aimed to determine the predicting role of mindfulness and difficulties in emotion regulation in addiction potential in university students. Method: This was a correlational study which falls within the category of descriptive studies. The sample included 180 students of Kashan Payame Noor University who were selected randomly and filled the Five Facet Mindfulness Qu...

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