BACKGROUND Particularly interesting new cysteine-histidine rich protein (PINCH), as an adapter protein of the LIM family for signal transduction in the integrin and growth factor pathway, is upregulated in the stroma of several common types of cancers and involved in promoting tumor progression. In the present study, we examined PINCH expression in normal endometrium, atypical endometrial hyper...

Particularly interesting new cysteine-histidine rich protein (PINCH), as a newly discovered protein of LIM family members, may play a role in signal transduction of integrin and growth factor, and involved in the incidence and development of tumors. PINCH protein is overexpressed in tumor-associated stroma of several types of tumors. However, there is no study of the PINCH in esophageal cancer,...

An explicit construction of pairing-friendly hyperelliptic curves with ordinary Jacobians was firstly given by D. Freeman. In this paper, we give other explicit constructions of pairing-friendly hyperelliptic curves. Our methods are based on the closed formulae for the order of the Jacobian of a hyperelliptic curve of type y = x + ax over a finite prime field Fp which are given by E. Furukawa, ...

Water systems often allow efficient water uses via water reuse and/or recirculation. Defining the network layout connecting water-using processes is a complex problem which involves several criteria to optimize, frequently accomplished using Water Pinch technology, optimizing freshwater flowrates entering the system. In this paper, a multiobjective optimization model considering two criteria is...

We compared the toe pinch force in men with and without type 2 diabetes mellitus (T2DM). Sixty-eight male T2DM patients and 35 apparently healthy men matched for age, sex, and body mass index (BMI) were enrolled in this cross-sectional study. We compared the toe pinch force between the subjects with and without T2DM, and we evaluated the effect of diabetic polyneuropathy on toe pinch force in t...

The purpose was to determine if pull-up performance was affected by the use of chalk (100% magnesium carbonate) during open-handed and pinch grip weight-assisted pull-ups (WAPU) in recreationally-trained rock climbers. Furthermore, the reliability of open-handed and pinch grip WAPU was also investigated. Recreationally-active volunteers (n = 9) completed six counterbalanced trials. Participants...

1. Introduction Implosion of surface waves and the resulting formation of a central vertical water jet happen often in nature; they also provide an important analogy for many physical phenomena. For example, when a heavy solid object impacts on a fluid surface, e.g. such as a meteoroid hitting the planet's ocean, a crater is created, which subsequently begins to pinch radially due to the pressu...

We present the results of a combined experimental and theoretical investigation of the vertical impact of a hydrophobic sphere with a water surface. Particular attention is given to characterizing the shape of the resulting air cavity in the low Bond number limit. A theoretical model is developed to describe the evolution of the cavity shape, and the pinch-off time is deduced for each of the th...

We apply the Cocks-Pinch method to obtain pairing-friendly composite order groups with prescribed embedding degree associated to ordinary elliptic curves, and we show that new security issues arise in the composite order setting.