This study tested if a therapeutic weight loss diet or presentation of diet to owners would influence owners’ assessment of their dog’s satiety. Twenty-three overweight, but otherwise healthy, dogs were fed their usual diet and then a study diet with both a positive and neutral description in a randomized crossover design. Diets were fed in amounts to meet dogs’ resting energy requirements to m...

Background: To study the effect of Nicotinic acid (Niacin) on body weight in NZW rabbits on atherogenic diet. Methods: In this experimental study, forty adult male New Zealand White (NZW) rabbits were randomly assigned to four groups A, B, C and D, each comprising ten rabbits. Group A served as Pure Control and received standard animal house diet (concentrated diet). Group B as treated control ...

OBJECTIVE A low-carbohydrate diet can reduce body weight and some cardiovascular disease (CVD) risk factors more than a low-fat diet, but differential adherence may play a role in these effects. METHODS Data were used from 148 adults who participated in a 12-month clinical trial examining the effect of a low-carbohydrate diet (<40 g/day) and a low-fat diet (<30% fat, <7% saturated fat) on wei...

BACKGROUND The effect of weight loss on different plasma lipid subclasses at the molecular level is unknown. The aim of this study was to examine whether a diet-induced weight reduction result in changes in the extended plasma lipid profiles (lipidome) in subjects with features of metabolic syndrome in a 33-week intervention. METHODOLOGY/PRINCIPAL FINDINGS Plasma samples of 9 subjects in the ...

objective(s):consumption of high-fat foods is one of the major causes of obesity. physical exercise is a strategy used to counteract obesity. the aim of this study was to investigate the effect of eight weeks endurance training and high-fat diet (hfd) on appetite-regulating hormones in rat plasma. materials and methods:twenty eight male wistar rats were randomly divided into four groups: contro...

PURPOSE Estrogens and androgens are elevated in obesity and associated with increased postmenopausal breast cancer risk, but the effect of weight loss on these biomarkers is unknown. We evaluated the individual and combined effects of a reduced-calorie weight loss diet and exercise on serum sex hormones in overweight and obese postmenopausal women. PATIENTS AND METHODS We conducted a single-b...

The use of high D(+)-fructose corn syrup has increased over the past several decades in the developed countries, while overweight and obesity rates and the related diseases have risen dramatically. However, we found that feeding a high D(+)-fructose diet (80% D(+)-fructose as part of the diet) to weaning rats for 21 days led to reduced food intake (50% less, P < 0.0001) and thus delayed the wei...

One of the mechanisms through which regular exercise contributes to weight maintenance could be by reducing intake and preference for high-fat (HF) diets. Indeed, we previously demonstrated that wheel-running rats robustly reduced HF diet intake and preference. The reduced HF diet preference by wheel running can be so profound that the rats consumed only the chow diet and completely avoided the...

Obesity promotes excessive inflammation, which is associated with senescence-like changes in visceral adipose tissue (VAT) and the development of type 2 diabetes (T2DM) and cardiovascular diseases. We have reported that a unique population of CD44hi CD62Llo CD4+ T cells that constitutively express PD-1 and CD153 exhibit cellular senescence and cause VAT inflammation by producing large amounts o...