BACKGROUND: Vertical transmission of HIV-1 is responsible for a high level of infant mortality necessitating early infant diagnosis. Serologic tests are not useful because of persistence of maternal antibodies in infants. Amplification of the integrated viral genome by PCR is the preferred method of diagnosis of HIV infection in these children. OBJECTIVE: To determine the prevalence of HIV amon...

A high performance liquid chromatographic method for simultaneous determination of isoniazid and acetyl isoniazid in urine was developed. Urine samples were filtered through Whatman number 1 filter paper and diluted filtrate was directly injected into C8 column (250mm). The mobile phase comprised of water and methanol in the ratio of 85:15. The analytes were detected at a wavelength of 274nm. T...