The immune system evolved to protect organisms from an infinite variety of disease-causing agents but to avoid harmful responses to self. However, such a powerf~l defense mechanism requires regulation. Immune regulation includes homeostatic and cellmediated targeted mechanisms to the activation, differentiation and function of antigen-triggered immuno-competent cells and irnmunoregulatory cells...

KWAN-DUN WU, DAVID BUNGARD, AND JONATHAN LYTTON Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan 100, Republic of China; Renal Division, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts 02115; and Departments of Biochemistry and Molecular Biology and Physiology & Biophysics, University of Calgary, Calgary...

Phytochemical and Pharmacological Profile of Withania somnifera Dunal: A ReviewQamar Uddin, L. Samiulla, V. K. Singh, S. Jamil

Le trichobezoard, etant une affection marqueepar la formation de concretions a partir cheveux, qui touche essentiellement des jeunes filles perturbees par desordres psychologiques. Nous rapportons un cas dune jeune fille, hospitalisee pour recidive trichobezoard. La fibroscopie gastrique pose le diagnostic, en general est facile presence dun contexte evocateur. Une exerese chirurgicale ete real...

Expression divergence is thought to be a hallmark of functional diversification between homologs post duplication. Modification in regulatory elements has been invoked to explain expression divergence after duplication for several MADS-box genes, however, verification of reciprocal loss of cis-regulatory elements is lacking in plants. Here, we report that the evolution of MPF2-like genes has en...

Withania coagulans (family: Solanaceae, English: Indian Cheese Maker, Hindi: Doda Paneer) fruit is known for its ethanopharmacological significance in health care system of India. Diet rich in high-fat is an important risk factor for diabetes, atherosclerosis and macro and microvascular complications. Treatment with aqueous extract of fruit of W. coagulans (aqWC; 250 mg/kg body weight) in chole...