نتایج جستجو برای: wnt2 protein

تعداد نتایج: 1234770  

2017
Hejia Yuan Shengqiang Yu Yuanshan Cui Changping Men Diandong Yang Zhenli Gao Zhe Zhu Jitao Wu

Mediator complex subunit 19 (Med19), a RNA polymerase II-embedded coactivator, is reported to be involved in bladder cancer (BCa) progression, but its functional contribution to this process is poorly understood. Here, we investigate the effects of Med19 on malignant behaviours of BCa, as well as to elucidate the possible mechanisms. Med19 expression in 15 BCa tissues was significantly higher t...

2010
Sabine Jurado Ian Smyth Bryce van Denderen Nora Tenis Andrew Hammet Kimberly Hewitt Jane-Lee Ng Carolyn J. McNees Sergei V. Kozlov Hayato Oka Masahiko Kobayashi Lindus A. Conlan Timothy J. Cole Ken-ichi Yamamoto Yoshihito Taniguchi Shunichi Takeda Martin F. Lavin Jörg Heierhorst

Zn²(+)-finger proteins comprise one of the largest protein superfamilies with diverse biological functions. The ATM substrate Chk2-interacting Zn²(+)-finger protein (ASCIZ; also known as ATMIN and ZNF822) was originally linked to functions in the DNA base damage response and has also been proposed to be an essential cofactor of the ATM kinase. Here we show that absence of ASCIZ leads to p53-ind...

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