The manuscript reports a study of Kr ion implantation in a Zn target in the 10-50 keV energy range at different source parameters, which combines experimental data and simulation with the SRIM package. The implanted thickness for the 45 keV was found to be 10 μm. The ion penetration depths for different films at different energies (10-50 keV) were calculated using SRIM computer program and foun...

background: there have been very few studies, with contradictory results, on the zinc status of children and adolescents with type-1 diabetes mellitus. the objective of this cross-sectional study was to determine zinc status based on the serum zinc concentration in type-1 diabetic children and adolescents and compare it with that of healthy controls. methods: thirty children and adolescents wit...

The complexation of zinc by natural organic ligands in the upper 600 m of the central North Pacific was determined with differential pulse anodic stripping voltammetry at a thin mercury film, rotating glassy-carbon disk electrode. Of the dissolved zinc in surface waters >98% was bound in strong complexes (log Klcond, =“z+ = 11 .O) by relatively zinc-specific organic ligands existing at low conc...

Mammalian metallothioneins are redox-active metalloproteins. In the case of zinc metallothioneins, the redox activity resides in the cysteine sulfur ligands of zinc. Oxidation releases zinc, whereas reduction re-generates zinc-binding capacity. Attempts to demonstrate the presence of the apoprotein (thionein) and the oxidized protein (thionin) in tissues posed tremendous analytical challenges. ...

Nanospray and collisionally-induced dissociation are used to evaluate the presence and absence of interstrand co-chelation of zinc ions in dimers of metallothionein. As was reported in a previous publication from this laboratory, co-chelation stabilizes the dimer to collisional activation, and facilitates asymmetrical zinc ion transfers during fragmentation. In the case of metallothionein, dime...

The oven, in which the diffusion runs were carried out, was built of a vertical glass tube with a Kanthal winding (see Fig. 1). This winding was supplied with some extra terminals; shunting parts of it allowed the temperature to be kept constant (or slightly increasing upwards) over a sufficient length in the oven. The insulation consisted of rockwool, a section of which could be removed tempor...

The metallo-beta-lactamases require divalent cations such as zinc or cadmium for hydrolyzing the amide bond of beta-lactam antibiotics. The crystal structure of the Zn2+ -bound enzyme from Bacteroides fragilis contains a binuclear zinc center in the active site. A hydroxide, coordinated to both zinc atoms, is proposed as the moiety that mounts the nucleophilic attack on the carbonyl carbon atom...

In this thesis, quantum chemical methods have been used to shed light on the reaction mechanisms of several dinuclear zinc enzymes. The enzymes studied are involved in the hydrolysis of phosphates, amides, and carboxylic esters, namely RNase Z, Dihydroorotase (DHO), and N-acyl homoserine lactone hydrolase (AHL lactonase). The density functional method B3LYP, together with quite large active sit...