Leishmaniasis is endemic in 88 countries throughout Africa, Asia, Europe and North and South America (Dedet et al., 2003). There are an estimated 12 million cases worldwide and there are about 1.5 million new cases of cutaneous leishmaniasis (CL) each year of which over 90% occur in Afghanistan, Algeria, Iran, Iraq, Saudi Arabia, Syria, Brazil and Peru (Ashford et al., 1992). Old World disease ...

The fossil record and systematics of murid rodents, reservoirs of zoonotic cutaneous leishmaniasis in the Palaearctic, Oriental, African, Nearctic and Neotropical, strongly support a Palaearctic origin of Leishmania. The fossil record and systematics of phlebotomine sand flies reinforce this idea. Interpretations of molecular data that place the origin of Leishmania in the Neotropical are incon...

background zoonotic cutaneous leishmaniasis (zcl) is polymorphic disease that may show various clinical manifestations. objectives this study investigates the determination of genetic variation within the species of leishmania major isolates from new cases in chabahar, a port city in southeast iran (situated at the iran-pakistan border). migration in this region indicates that leishmaniasis is ...

background: to clinically characterize the cutaneous leishmaniasis and identify the causative parasite species in mirjaveh, an important geographical region across the border of iran-pakistan at southeast of iran. methods: a number of 116 patients during a year since march 2005 to april 2006, subjected to the study. clinical infor­mation collected and scrapings were taken from cutaneous lesions...

Great gerbils (Rhombomys opimus) are the most common gerbils in center to northeast of Iran as well as central Asia and serve as reservoirs for the zoonotic agents, including Leishmania major, the principal etiologic agent of zoonotic cutaneous leishmaniasis (ZCL). The outcome of L. major infection in gerbils is not uniform. Among several immune-related factors including cytokine genes, the pol...

BACKGROUND & OBJECTIVES Phlebotomine sandflies (Diptera: Psychodidae) play main role in the transmission of different forms of leishmaniasis in the world. Phlebotomus papatasi is the main vector of zoonotic cutaneous leishmaniasis (ZCL) in Iran. There are several control measures for vector control using different classes of insecticides. The aim of this study was to breed the sandflies which w...

Leishmaniasis is a well-documented disease of humans and animals worldwide. In humans, leishmaniasis is generally zoonotic with a number of different clinical manifestations ranging from single or multiple skin lesions (cutaneous leishmaniasis) to destruction of the mucosae, including the soft cartilage of the nasal septum (mucocutaneous leishmaniasis) or systemic infections of the liver and sp...

background: cutaneous leishmaniasis (cl) is one of the most important neglected tropical diseases and a major public health challenge in iran caused by leishmania spp and transmitted by phlebotomine sand flies. the number of cl cases has shown an increasing pattern all over the country, including the district of varamin, southeast of tehran, iran. this study aimed to identify the leishmania spp...

background: zoonotic cutaneous leishmaniasis (zcl) is an expanding disease and public health problem in iran. in the current study, natural leishmania infection rate and seasonal fluctuation of the infection in rhombomys opimus population of a hyperendemic focus of zcl in iran was investigated. methods:   the study was conducted from october 2006 to october 2008 in esfahan province, central par...