BACKGROUND AND PURPOSE TNF-α is an inflammatory cytokine implicated in the pathogenesis of asthma and it causes airway inflammation, bronchoconstriction and airway hyperresponsiveness to a number of spasmogens following inhalation. EXPERIMENTAL APPROACH We compared contractions of guinea pig isolated trachea incubated with saline or TNF-α for 1, 2 or 4 days to electrical field stimulation (EF...

In this paper, we introduce three classes of proximal contractions that are called the proximally λ−ψ−dominated contractions, generalized ηβγ−proximal and Berinde-type weak obtain common best proximity points for these in setting F−metric spaces. Further, point result α−φ−proximal As an application, fixed coincidence results obtained. Some examples provided to support validity our main results....

In this paper, using α—admissibility and the concept of simulation functions, some near-fixed point results in setting metric interval normed spaces are established. The have been proved Z-contractions.

In this paper, we establish the existence and uniqueness of a fixed point (α, β)-admissible almost z-contractions via simulation functions in metric-like spaces. Our results generalize unify several theorem literature.

The purpose of this work is to investigate the existence of fixed points of some mappings in fixed point theory by combining some important concepts which are F-weak contractions, multivalued mappings, integral transformations and α-admissible mappings. In fixed point theory, it is important to find fixed points of some classess under F- or F-weak contractions. Also multivalued mappings is the ...

Defensins, cysteine-rich cationic polypeptides released from neutrophils, are known to have powerful antimicrobial properties. In this study, we sacrificed 30 rats to investigate the effects of α-defensin 1 on detrusor muscle contractions in isolated rat bladder. From the experiments we found relaxing effects of α-defensin 1 on the contractions induced by phenylephrine (PE) but not by bethanech...