background and objectives: the genus johrenia belongs to umbelliferae family and contains five species that are endemic to iran. johrenia paucijuga grows widely in the north-west, west and center of iran. so far, there has been no research about phytochemistry of j. paucijuga. in the present study, phytochemicals of the plants have been isolated and their structures have been elucidated. method...

The essential oil of Salvia aegyptiaca was analysed by GC/ MS technique. Eighteen compounds were identified. It was found that the essential oil comprises 40% terpenoidal constituents, opposite to 32% fat derivatives. The major terpenoidal component was 1(10)aristolene (19.3%). From the non-volatile matter, β-amyrin, lupeol, β-sitosterol, stigmasterol, β-sitosterol-β-D-glucopyranoside and stigm...

Amyloid-β (Aβ), major constituent of senile plaques in Alzheimer's disease (AD), is generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Several lipids, especially cholesterol, are associated with AD. Phytosterols are naturally occurring cholesterol plant equivalents, recently been shown to cross the blood-brain-barrier accumulating in brain. Here, w...

Background The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells. Methods Phytosterols (e.g., stigmasterol and β-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed using high-performance liquid chromatography. The P. ginseng roots analyzed in this study were coll...

Sterols play a key role in various physiological processes of plants. Commonly, stigmasterol, β-sitosterol and campesterol represent the main plant sterols, cholesterol is often reported as trace sterol. Changes especially β-sitosterol/stigmasterol levels, can be induced by different biotic abiotic factors. Plant parasitic nematodes, such root-knot nematode Meloidogyne incognita, are devastatin...

The Cactaceae family is composed by 124 genera and about 1438 species. Pilosocereus gounellei, popularly known in Brazil as xique-xique, is used in folk medicine to treat prostate inflammation, gastrointestinal and urinary diseases. The pioneering phytochemical study of P. gounellei was performed using column chromatography and HPLC, resulting in the isolation of 10 substances: pinostrobin (1),...

Abstract Background Sterols are structural and functional components of eukaryotic cell membranes. Plants produce a complex mixture sterols, among which β-sitosterol, stigmasterol, campesterol, cholesterol in some Solanaceae, the most abundant species. Many reports have shown that stigmasterol to β-sitosterol ratio changes during plant development response stresses, suggesting it may play role ...

Background and objectives: The genus Johrenia belongs to Umbelliferae family and contains five species that are endemic to Iran. Johrenia paucijuga grows widely in the north-west, west and center of Iran. So far, there has been no research about phytochemistry of J. paucijuga. In the present study, phytochemicals of the plants have been isolated and their structures h...

Here we use nuclear magnetic resonance to measure the solubility limit of several biologically relevant sterols in electroformed giant unilamellar vesicle membranes containing phosphatidylcholine (PC) lipids in ratios of 1:1:X DOPC:DPPC:sterol. We find solubility limits of cholesterol, lanosterol, ergosterol, stigmasterol, and β-sitosterol to be 65-70%, ~35%, 30-35%, 20-25%, and ~40%, respectiv...

Thirteen fatty acids were identified from the pulps of four Tunisian Ziziphus jujuba ecotypes (Sfax, Choutrana, Mahres and Mahdia), using capillary gaseous chromatography method. These oils presented 8.31% to 12.35% of dry weights. Compared to the other ecotypes, Mahres and Choutrana were the richest of the oleic acid. The palmitic acid was the most important compound of the Sfax ecotype. Unsat...