Phosphatidylserine (PS) externalization is a marker for the nucleated cell apoptosis, and refers cellular activation rather than apoptosis in platelets. On the other hand, several similarities exist between platelet activation and apoptosis in nucleated cells. Herewith we investigated the relationship between platelet activation and platelet apoptosis. Platelets isolated from fresh blood of 22 ...

The methodology described in this article was developed to transcend the limitations of both approaches. Its goal is to use existing data to identify small areas with high levels of adolescent childbearing. The method is an active approach to identify what can be defined as “hot spots” for adolescent births, even when they are located in counties or communities where adolescent births are not c...

Tooth root formation is initiated by the elongation of Hertwig’s epithelial root sheath (HERS). HERS cells are widely accepted to control root formation, but the mechanisms regulating HERS growth have not been elucidated. To solve this problem, we have established a new culture method for postnatal mouse mandibular molars and, using it, examined the role of insulin-like growth factor-I (IGF-I) ...

RAPID EYE MOVEMENT (REM) SLEEP BEHAVIOR DISORDER (RBD) IS A PARASOMNIA CHARACTERIZED BY DREAM-ENACTING BEHAVIORS RELATED TO LOSS OF the normal generalized skeletal muscle atonia during REM sleep1,2. RBD may be idiopathic or associated with neurodegenerative diseases such as Parkinson’s disease3, multiple system atrophy4, dementia with Lewy bodies5, Machado-Joseph disease6 and parkinsonism with ...

host defenses allow varying types of infection. Candidal infections offer a clear example of this point. Granulocytes primarily prevent bloodborne candidiasis, and this becomes apparent in neutropenic patients, who are at greater risk to develop Candida-induced fungemia and sepsis. Contrast this situation with the T-cell–mediated defense that prevents mucosal Candida proliferation. This propert...

In this study, we investigate the relationship between uncertainty and trust in exogenous shifts in modes of social exchange (i.e., those that are not initiated by the individuals in a given exchange system). We explore how transitions from a high uncertainty environment (reciprocal exchange) to lower-uncertainty environments (nonbinding or binding negotiated exchange) affect the level of trust...

been a lightning rod for opponents. Title X funds are distributed directly by the federal government to a range of grantees, which include state agencies as well as nonprofit organizations such as Planned Parenthood affiliates and regional family planning councils. Title X funds are distributed in all states. Two major federal block grants, the maternal and child health (MCH) and the social ser...