OBJECTIVES This study sought to determine the immediate and long-term effects of intraplaque hemorrhage (IPH) on plaque progression in the carotid artery. BACKGROUND Previous studies have associated IPH in the carotid artery with more rapid plaque progression. However, the time course and long-term effect remain unknown. Carotid magnetic resonance imaging is a noninvasive imaging technique th...

BACKGROUND AND PURPOSE Carotid IPH can be detected with MR imaging. The aim of this study was to determine the safety of CAS using an emboli protection device in patients with severe carotid artery stenosis and MR imaging-depicted carotid IPH. MATERIALS AND METHODS We retrospectively reviewed a prospective data base that included 91 consecutive patients with severe carotid stenosis and high-r...

Both cryptogenic liver cirrhosis and idiopathic portal hypertension without pathological findings of liver cirrhosis (IPH) are relatively common in Japan. To find differrence between IPH and cryptogenic liver cirrhosis of Japanese, we investigated human leukocyte antigen (HLA), familial clustering of liver diseases as well as prevalence of HBs antigen in 31 patients with IPH. The age of patient...

Vulnerable atherosclerotic plaque in carotid arteries is a major cause of cerebrovascular events, such as transient ischemia attack and ischemic stroke. Previous studies have shown that compositional characteristics, particularly intraplaque hemorrhage (IPH) and lipid-rich necrotic core, in carotid artery plaques play a key role in plaque vulnerability. In particular, it is increasingly evidenc...

BACKGROUND AND PURPOSE The main objective of this study was to evaluate CT angiographic (CTA) features that are able to predict the presence of intraplaque hemorrhage (IPH) as defined by MR-IPH. METHODS One hundred sixty-seven consecutive patients (mean age 69 years, SD 12.8; 58 females) underwent both MR-IPH and CTA within 3 weeks. MR-IPH, the gold standard, was performed at 1.5 T using a ne...

In the course of acquiring their first language, infants decompose continuous speech into relevant structural units such as clauses and words. Gleitman & Wanner (1982) have suggested, within the framework of prosodic bootstrapping, that infants approach this segmentation problem by exploiting acoustic information in the speech signal which correlates with the occurrence of syntactically signifi...

BACKGROUND Though multiple single nucleotide polymorphisms (SNPs) associated with type 2 diabetes have been identified, the genetic bases of isolated fasting hyperglycaemia (IFH) and isolated postprandial hyperglycaemia (IPH) were still unclear. In present study, we aimed to investigate the association of genome-wide association study-validated genetic variants and IFH or IPH in Han Chinese. ...

BACKGROUND Intraplaque hemorrhage (IPH) is associated with atherosclerosis progression and subsequent cardiovascular events. We sought to develop a semi-automatic method with an optimized threshold for carotid IPH detection and quantification on MP-RAGE images using matched histology as the gold standard. METHODS Fourteen patients scheduled for carotid endarterectomy underwent 3D MP-RAGE card...

We report on the photo-conductivity studies of chemically synthesized graphene quantum dots (GQDs) of average size 12 nm obtained by the oxidative acid treatment of MWCNTs. The dependence of photocurrent Iph (Iph = Iill - Idark) on the laser intensity P under a wide range of laser intensities (5 mW ≤ P ≤ 60 mW) shows a fractional power dependence of Iph on light intensity. The temperature depen...