نتایج جستجو برای: سکانس mtc

تعداد نتایج: 2202  

ژورنال: :مجله دانشگاه علوم پزشکی همدان 0
نازنین فرشچیان n. farshchian دانشگاه علوم پزشکی کرمانشاه نازنین رزازیان n. razazian دانشگاه علوم پزشکی کرمانشاه منصور رضایی m. rezaei دانشگاه علوم پزشکی کرمانشاه عبدالله نورزاده a. noorzadeh دانشگاه علوم پزشکی کرمانشاه

مقدمه و هدف: ms یکی از شایعترین اختلالات عصبی ناتوان کننده می باشد. تشخیص پلاک فعال جدید ms در تعیین شروع حمله و بررسی وضعیت کلینیکی و شروع سریعتر درمان و ارزیابی پاسخ به درمان بسیار مهم است و mri با کنتراست بهترین اندیکاتور در این زمینه است. هدف از این مطالعه بررسی ارزش mtc بدون تزریق در تشخیص پلاکهای فعال ms است. روش کار: این مطالعه از نوع مقطعی است و بر روی 62 بیمار که دارایms  شناخته شده بو...

ژورنال: :مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 0
سارا شیخ الاسلامی sara sheikholeslami cellular and molecular research center, obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran.مرکز تحقیقات سلولی و مولکولی، مرکز تحقیقات چاقی، پژوهشکده غدد درون ریز و متابولیسم دانشگاه علوم پزشکی شهید بهشتی مرجان ظریف یگانه marjan zarif yeganeh cellular and molecular research center, obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran.مرکز تحقیقات سلولی و مولکولی، مرکز تحقیقات چاقی، پژوهشکده غدد درون ریز و متابولیسم دانشگاه علوم پزشکی شهید بهشتی لاله حقوقی راد laleh hoghooghi rad cellular and molecular research center, obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran.مرکز تحقیقات سلولی و مولکولی، مرکز تحقیقات چاقی، پژوهشکده غدد درون ریز و متابولیسم دانشگاه علوم پزشکی شهید بهشتی مریم سادات دانشپور maryam sadat daneshpour cellular and molecular research center, obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran.مرکز تحقیقات سلولی و مولکولی، مرکز تحقیقات چاقی، پژوهشکده غدد درون ریز و متابولیسم دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران. مهدی هدایتی mehdi hedayati cellular and molecular research center, obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, no. 24, parvaneh street, yaman st., velenjak, chamran highway, tehran, iran. postal code: 198571741تهران، بزرگراه شهید چمران، ولنجک، خ یمن، ابتدای خیابان پروانه، پلاک 24، پژوهشکده علوم غدد درون ریز و متابولیسم، مرکز تحقیقات چاقی، مرکز تحقیقات سلولی و مولکولی، کدپستی: 1985717413 تلفن: 22432500-021

زمینه و هدف: سرطان مدولاری تیرویید (mtc) به دو شکل اسپورادیک (75%) موارد و ارثی (25%) بروز می کند. اثر جهش های بد معنی پروتوآنکوژن ret در پیشرفت بیماری به خوبی مشخص شده است. هدف از انجام این مطالعه بررسی هاپلوتایپ g691s/s904s در بیماران mtc و خانواده آنها بود. روش بررسی: مطالعه حاضر در طی سال های 1393-1383 در مرکز تحقیقات سلولی و مولکولی پژوهشکده غدد درون ریز و متابولیسم دانشگاه علوم پزشکی شهید...

Journal: :acta medica iranica 0
nastaran sabetkish department of pathology, shariati hospital, tehran university of medical sciences, tehran, iran. seyyed mohammad tavangar department of pathology, shariati hospital, tehran university of medical sciences, tehran, iran.

the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.

Journal: :cell journal 0
masoumeh mohammadi mehdi hedayati

approximately 5-10% of all thyroid cancers are medullary thyroid carcinomas (mtc). mtc is mainly sporadic in nature, but 20-30% of cases are hereditary. genetic testing for hereditary mtc is very important for the patient and his family, but the patients must be receiving appropriate genetic counseling. about 98% of patients with hereditary mtc have germline mutations in exons 10, 11, 13, 14, 1...

Journal: :medical journal of islamic republic of iran 0
iraj nabipour from the endocrine research center; shaheed beheshti university of medical sciences, tehran, the persian gulf health research center; bushehr university of medical sciences, bushehr and the endocrine research center, tehran university of medical sciences, tehran, iran. fatemeh haji-ghasemi shahriar kiai reza baradar-jalili fereidoun azizi

meduiiary thyroid carcinoma (mtc) occurs both sporadically and in the autosomal dominantly inherited multiple endocrine neoplasia (men) type 2 syndromes. the distinction between true sporadic mtc and a new mutation familial case is important for future clinical management of both the patient and family. the susceptibility gene for hereditary mtc is the ret proto-oncogene. dna analysis for germl...

Journal: :iranian journal of public health 0
sara sheikholeslami cellular and molecular research center, research institute for endocrine sciences, obesity research center, shahid beheshti university of medical sciences , tehran, iran. marjan zarif yeganeh cellular and molecular research center, research institute for endocrine sciences, obesity research center, shahid beheshti university of medical sciences , tehran, iran. laleh hoghooghi rad cellular and molecular research center, research institute for endocrine sciences, obesity research center, shahid beheshti university of medical sciences , tehran, iran. hoda golab ghadaksaz cellular and molecular research center, research institute for endocrine sciences, obesity research center, shahid beheshti university of medical sciences , tehran, iran. mehdi hedayati cellular and molecular research center, research institute for endocrine sciences, obesity research center, shahid beheshti university of medical sciences , tehran, iran.

medullary thyroid carcinoma (mtc) occurs in both sporadic (75%) and hereditary (25%) forms. the missense mutations of the rearranged during transfection (ret) proto-oncogene in mtc development have been well demonstrated. the aim of this study was to investigate frequency of g691s/s904s haplotype in mtc patients and their relatives.in this research 293 participants were studied, including 181 p...

Introduction: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare.  Case Report: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year-old woman. In 2010, she underwent total thyroidectomy and right-sided modified radical neck dis...

Journal: :Cancer cell 2013
Karine Pozo Emely Castro-Rivera Chunfeng Tan Florian Plattner Gert Schwach Veronika Siegl Douglas Meyer Ailan Guo Justin Gundara Gabriel Mettlach Edmond Richer Jonathan A Guevara Li Ning Anjali Gupta Guiyang Hao Li-Huei Tsai Xiankai Sun Pietro Antich Stanley Sidhu Bruce G Robinson Herbert Chen Fiemu E Nwariaku Roswitha Pfragner James A Richardson James A Bibb

Medullary thyroid carcinoma (MTC) is a neuroendocrine cancer that originates from calcitonin-secreting parafollicular cells, or C cells. We found that Cdk5 and its cofactors p35 and p25 are highly expressed in human MTC and that Cdk5 activity promotes MTC proliferation. A conditional MTC mouse model was generated and corroborated the role of aberrant Cdk5 activation in MTC. C cell-specific over...

2014
Pierpaolo Trimboli Luca Giovanella Stefano Valabrega Massimiliano Andrioli Roberto Baldelli Nadia Cremonini Fabio Rossi Leo Guidobaldi Agnese Barnabei Francesca Rota Antonella Paoloni Laura Rizza Giorgio Fattorini Maurizio Latini Claudio Ventura Paolo Falasca Fabio Orlandi Anna Crescenzi Ferdinando D’Ambrosio Vito Cantisani Francesco Romanelli Roberto Negro Enrico Saggiorato Marialuisa Appetecchia

BACKGROUND Poor prognosis of medullary thyroid cancer (MTC) with suspicious ultrasound (US) features has been reported. The aim of the study was to investigate the association between preoperative US presentation and aggressiveness features of MTC. Also, US features of MTC were compared with those previously reported. METHODS Study group comprised 134 MTC from nine different centers. Based on...

2014
TARIK TALEB

Machine type communications (MTCs) enable the communications of machines (devices) to machines over mobile networks. Besides simplifying our daily lives, the MTC business represents a promising market for mobile operators to increase their revenues. However, before a complete deployment of MTC over mobile networks, there is need to update the specifications of mobile networks in order to cope w...

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