Background: Ligands of chemokine receptor CCR5, including MIP-1a, MIP-1b, and RANTES, have been implicated in rheumatoid arthritis. Objective: To test whether CCR5 d32 polymorphism has a negative association with rheumatoid arthritis in a New Zealand cohort. Methods: 516 white patients with rheumatoid arthritis and 985 healthy controls were investigated by PCR amplification of the region flanki...

سابقه و هدف: آب هوای یک منطقه در دوره بلندمدت را اقلیم گویند. شناسایی طبقه‌بندی اقلیمی از دیرباز مورد توجه متخصصان هواشناسی بوده است. محققان با به کارگیری روش ­های مختلف استفاده متغیرهای همچون بارش دما، زمین مناطق همگن طبقه ­بندی کرده‌اند نتایج پهنه‌بندی ارزیابی کمبود منابع مقیاس­ های کوچک بزرگ منظور پیش‌بینی اقدامات عملی برای کنترل خشکی آسیب‌پذیر به‌کار برده‌اند. هدف این تحقیق به‌‌روزرسانی تحل...

The chemokine (CK) receptor 5 (CCR5) is necessary for two adjacent cysteines (CC)-CKs such as Regulated upon Activation Normal T cell Expressed and Secreted, a/o Macrophage Inflammatory Protein 1alpha/beta to mediate their inflammatory properties. The CCR5 gene polymorphism with 32-basepair deletion (d32) leads to receptor inactivation/dysfunction in homo/heterozygous individuals. We have evalu...

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-D32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-D32 arose within the past 1,000 y and rose to its present high frequency (5%–14%) in Europe as a result of strong positive selection, perhaps by such selective agents as the bubonic plague or smallpox during the Middle Ages...

مقولات ابزار ذهن ما برای شناخت حقایق اطراف است. بشر اشیای خارجی یا مفاهیم ناظر به آن‌ها را ذیل یکی از قرار داده است و فهم می‌کند. اما میزان صدق بر تمام واقعیات هستی هنوز درستی مشخص نیست. آنچه در آرای برخی فلاسفة مشاء دیده می‌شود‌این که پیرو آن انواعی آنها‌ایجاد می‌شود نقش تعیین کننده تعین نوعی موجودات دارند صرفاً طبقه بندی انسان نیستند. در‌این میان ملاصدرا دیدگاه متفاوتی آراء خود نشان می‌دهد محد...

Background: Homozygosity (D32/D32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease progression. Methodology/Principal Findings: We genotyped a population of 737 HIV-positive adults and 463 healthy controls for the CCR5D32 deletion and found heterozygous freque...

The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the world. We investigated the distribution of the CCR5 coding region alleles in Sout...

A systematic experimental study of the effect of several factors on the mean drop diameter, d32, during emulsification, is performed with soybean oil-in-water emulsions. These factors are (1) type of used emulsifier; (2) emulsifier concentration, CS; and (3) ionic strength of the aqueous solution. Three different types of emulsifier, anionic (sodium dodecyl sulfate, SDS), nonionic (polyoxyethyl...

The aim of this work is to understand the effects of the rheological and interfacial properties of a model food on continuous foaming operation in laminar flow conditions. The rheological properties of food model (glucose syrup) were adjusted using three polysaccharides: xanthan, LM pectin and guar. Interfacial properties were varied using two kinds of proteins: Na-caseinates and whey proteins ...