In this paper LQG controller for TRMS without and with sensor, actuator failure is designed. Implementation of LQG controller for TRMS is done under no failure of sensor, actuator. TRMS output with LQG controller and reliable H infinity controller are compared without and with sensor, actuator failure. The objective of the proposed technique is to prove the H infinity controller is reliable ove...

In this paper, twin rotor multi input multi output system (TRMS) is considered as a prototype laboratory set-up of helicopter. The aim of studying the model of TRMS and designing the controller for it is to provide a platform for controlling the flight of helicopter. An optimal state feedback controller based on linear quadratic regulator (LQR) technique has been designed for twin rotor multi i...

UNLABELLED In eukaryotes, gene expression is controlled by various transcription factors that bind to the promoter regions. Transcription factors may act positively, negatively or not at all. Different combinations of them may also activate or repress gene expression, and form regulatory networks of transcription. Uncovering such regulatory networks is a central challenge in genomic biology. In...

Impaired GABAergic inhibitory neurotransmission plays an essential role in the pathogenesis of epilepsy. GABA(A) receptor (GABA(A)R), potassium chloride cotransporter 2 (KCC2) and astrocytes are of particular importance to GABAergic transmission and thus involved in the development of increased seizure susceptibility. The tremor rat (TRM: tm/tm), a genetic mutant discovered in a Kyoto-Wistar co...

Twin rotor MIMO system (TRMS) are widely used in the aerospace application. TRMS consist of two rotors one is for the horizontal moment and other for the vertical moment. These two rotors are attached on a beam for the counter balance, which ensures the safety of the helicopter. For controlling the TRMS mechanical parts and electrical circuitry are used together. In this paper multi-objective g...

This paper presents a comparative study of neural observers for TRMS. These are Chebyshev neural network based observer (CNN) and Multi-layer feedforward neural network (MLFFNN) observer. TRMS is a highly non-linear system having mutual interference between two rotors, it is trivial to design an effective controller for the TRMS to reach the desirable yaw and pitch angles. All the states are no...

Invasive fungal infections result in high morbidity and mortality. Host organs targeted by fungal pathogens vary depending on the route of infection and fungal species encountered. Cryptococcus neoformans infects the respiratory tract and disseminates throughout the central nervous system. Candida albicans infects mucosal tissues and the skin, and systemic Candida infection in rodents has a tro...

How tissue-resident macrophages (TRM) impact adaptive immune responses remains poorly understood. We report novel mechanisms by which TRMs regulate T cell activities at tissue sites. These mechanisms are mediated by the complement receptor of immunoglobulin family (CRIg). Using animal models for autoimmune type 1 diabetes (T1D), we found that CRIg+ TRMs formed a protective barrier surrounding p...

Moderate wine consumption has been shown to reduce cardiovascular (CV) risk, due to alcohol and polyphenolic compounds, such as resveratrol. We investigated the associations between total urinary resveratrol metabolites (TRMs) as biomarkers of wine and resveratrol consumption and CV risk factors in a large cross-sectional study including high CV risk individuals in Spain. We studied 1000 partic...