نتایج جستجو برای: ‌BMCS

تعداد نتایج: 348  

2016
Qingzhen Gao Xiaoping Wang Ruibin Zhang Pu Wang Yongsheng Jing Wanjun Ren Bin Zhu

AIMS/INTRODUCTION The study aimed to compare the impact of allogeneic bone marrow cells (BMCs) infusion through the inferior vena cava (IVC) and portal vein (PV) combined with rapamycin on allogeneic islet grafts in diabetic rats. MATERIALS AND METHODS Recipient diabetic Wistar rats were infused with islets from Sprague-Dawley rats through the PV. PKH26-labeled BMCs of Sprague-Dawley rats wer...

2014
Yong Sook Kim Hea Jin Kang Moon Hwa Hong Wan Seok Kang Nakwon Choe Hyun Kook Myung Ho Jeong Youngkeun Ahn

BACKGROUND AND OBJECTIVES Diabetes is reported to reduce the function or number of progenitor cells. We compared the gene expression patterns of bone marrow-derived mesenchymal stem cells from diabetic (DM-BMCs) and healthy (non-DM-BMCs) rats and suggested Angiopoietin-like 4 (Angptl4) could be a responsible factor for impaired angiogenesis of DM-BMCs. SUBJECTS AND METHODS BMCs were isolated ...

2013
Lanfang Li Heng Zeng Xuwei Hou Xiaochen He Jian-Xiong Chen

Our previous study shows that treatment with apelin increases bone marrow cells (BMCs) recruitment and promotes cardiac repair after myocardial infarction (MI). The objective of this study was to investigate whether overexpression of apelin in BMCs improved cell therapy and accelerated cardiac repair and functional recovery in post-MI mice. Mouse myocardial infarction was achieved by coronary a...

Journal: :Advances in Applied Probability 2022

Abstract Bifurcating Markov chains (BMCs) are indexed by a full binary tree representing the evolution of trait along population where each individual has two children. We provide central limit theorem for additive functionals BMCs under $L^2$ -ergodic conditions with three different regimes. This completes pointwise approach developed in previous work. As an application, we study elementary ca...

Journal: :Journal of molecular endocrinology 2007
Tomoko Tanaka Shigeki Gondo Taijiro Okabe Kenji Ohe Hisao Shirohzu Hidetaka Morinaga Masatoshi Nomura Kenzaburo Tani Ryoichi Takayanagi Hajime Nawata Toshihiko Yanase

Steroidogenic factor 1/adrenal 4 binding protein (SF-1/Ad4BP) is an essential nuclear receptor for steroidogenesis as well as for adrenal and gonadal gland development. Mesenchymal bone marrow cells (BMCs) contain pluripotent progenitor cells, which differentiate into multiple lineages. In a previous study, we reported that adenovirus-mediated forced expression of SF-1 could transform mouse pri...

2007
Masayuki Kubo Tao-Sheng Li Ryo Suzuki Mako Ohshima Shu-Lan Qin Kimikazu Hamano

Kubo M, Li T-S, Suzuki R, Ohshima M, Qin S-L, Hamano K. Short-term pretreatment with low-dose hydrogen peroxide enhances the efficacy of bone marrow cells for therapeutic angiogenesis. Am J Physiol Heart Circ Physiol 292: H2582–H2588, 2007. First published February 2, 2007; doi:10.1152/ajpheart.00786.2006.—Therapeutic angiogenesis can be induced by the implantation of bone marrow cells (BMCs). ...

Journal: :American journal of physiology. Heart and circulatory physiology 2007
Masayuki Kubo Tao-Sheng Li Ryo Suzuki Mako Ohshima Shu-Lan Qin Kimikazu Hamano

Therapeutic angiogenesis can be induced by the implantation of bone marrow cells (BMCs). Hydrogen peroxide (H(2)O(2)) has been shown to increase VEGF expression and to be involved in angiogenesis. We tested the hypothesis that pretreatment with H(2)O(2) enhances the efficacy of BMCs for neovascularization. H(2)O(2) pretreatment was done by incubating mouse BMCs in 5 microM H(2)O(2) for 30 min, ...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
Florian H Seeger Tina Rasper Masamichi Koyanagi Henrik Fox Andreas M Zeiher Stefanie Dimmeler

OBJECTIVE Bone marrow-derived mononuclear cells (BMCs) improve the functional recovery after ischemia. However, BMCs comprise a heterogeneous mixture of cells, and it is not known which cell types are responsible for the induction of neovascularization after cell therapy. Because cell recruitment is critically dependent on the expression of the SDF-1-receptor CXCR4, we examined whether the expr...

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2012
Masayuki Kubo Tao-Sheng Li Hiroshi Kurazumi Yoshihiro Takemoto Mako Ohshima Tomoaki Murata Shunsaku Katsura Noriyasu Morikage Akira Furutani Kimikazu Hamano

BACKGROUND Hypoxic preconditioning of bone marrow cells (BMCs) from young healthy individuals can enhance the cells' therapeutic potential. Considering that the response to hypoxia may differ according to the quality of the cells, we assessed the effect of hypoxic preconditioning on BMCs from aged mice and compared the difference in response between BMCs from aged and young mice. METHODS AND ...

Journal: :Circulation 1999
S Tomita R K Li R D Weisel D A Mickle E J Kim T Sakai Z Q Jia

BACKGROUND Autologous bone marrow cells (BMCs) transplanted into ventricular scar tissue may differentiate into cardiomyocytes and restore myocardial function. This study evaluated cardiomyogenic differentiation of BMCs, their survival in myocardial scar tissue, and the effect of the implanted cells on heart function. METHODS AND RESULTS IN VITRO STUDIES BMCs from adult rats were cultured ...

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