Continuous experiments were conducted to study the influence of pH in the range 4.0–6.5 on the acidification of dairy wastewater at 37°C with 12 hours of hydraulic retention in an upflow reactor. Results showed that degradation of dairy pollutants increased with pH from pH 4.0 to 5.5. At pH 5.5, 95% of carbohydrate, 82% of protein and 41% of lipid were degraded. Based on chemical oxygen demand ...

PURPOSE The aim of this study was to investigate the therapeutic effects of a herbal formula, PerioH-035, containing Angelica sinensis, steamed Rehmannia glutinosa, Angelica dahurica, Cimicifuga heracleifolia, and Zanthoxylum piperitum on the periodontal breakdown in a well-established ligature-induced periodontitis model in rats. METHODS Sprague-Dawley rats were randomly assigned to 1 of 4 g...

We have shown recently that estrogen receptor (ER) ligands share a diphenyl ethane pharmacophore with Sah 58-035 [3-[decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]-propanamide], a prototypical inhibitor of the acyl-cholesterolacyl-transferase (ACAT), which enabled us to establish that ER ligands were potent inhibitors of ACAT and blocked the formation of foam cells. In the present stu...

We examined the effect of acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitors on intracellular cholesterol stores in primary human monocyte-derived macrophages (HMMs) during foam cell formation. HMMs were exposed to acetylated low density lipoprotein (acLDL, 500 microg protein per mL) with or without 58-035 (1 to 10 microg/mL) or CI-976 (2 microg/mL) for 2 to 48 hours. Total cholester...

Cholesteryl ester accumulation in arterial wall macrophages (foam cells) is a prominent feature of atherosclerotic lesions. We have previously shown that 5774 macrophages accumulate large amounts of cholesteryl ester when incubated with unmodified low density lipoprotein (LDL) and that this is related to sluggish down-regulation of the 5774 LDL receptor and 3hydroxy-3-methylglutaryl-coenzyme A ...

Aims. An asteroseismological study of PG 1159−035, the prototype of the GW Vir variable stars, has been performed on the basis of detailed and full PG1159 evolutionary models presented by Miller Bertolami & Althaus (2006). Methods. We carried out extensive computations of adiabatic g-mode pulsation periods on PG1159 evolutionary models with stellar masses spanning the range 0.530 to 0.741M⊙. Th...

With 10m class telescopes as well as with time-tagging detectors on board of HST and FUSE, the analysis of time-resolved spectra for pulsating white dwarfs becomes feasible. We present simulated time-resolved spectra for the hot pulsating white dwarf PG 1159-035 and compare these models with observational data of the 516 s mode based on HST-STIS spectroscopy. A determination of the pulsation mo...