GDC-0425 [5-((1-ethylpiperidin-4-yl)oxy)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile] is an orally bioavailable small-molecule inhibitor of checkpoint kinase 1 that was investigated as a novel cotherapy to potentiate chemotherapeutic drugs, such as gemcitabine. In a radiolabeled absorption, distribution, metabolism, and excretion study in Sprague-Dawley rats, trace-level but long-lived 14...

The antimicrobial and antiplasmid activities of essential oils (orange oil, eucalyptus oil, fennel oil, geranium oil, juniper oil, peppermint oil, rosemary oil, purified turpentine oil, thyme oil, Australian tea tree oil) and of menthol, the main component of peppermint oil, were investigated. The antimicrobial activities were determined on the Gram (+) Staphylococcus epidermidis and the Gram (...

We extend the recently proved relation between certain models of Non-Riemannian gravitation and Einstein-Proca-Weyl theories to a class of Scalar gravity theories, this is used to present a Black-Hole Dilaton solution with non-Riemannian connection. PACS numbers: 04.20J, 0450, 0425.Dm, 04.40.Nr, 0470-s permanent address, e-mail: [email protected]

We extend the recently proved relation between certain models of Non-Riemannian gravitation and Einstein-Proca-Weyl theories to a class of Scalar gravity theories, this is used to present a Black-Hole Dilaton solution with non-Riemannian connection. PACS numbers: 04.20J, 0450, 0425.Dm, 04.40.Nr, 0470-s permanent address, e-mail: [email protected]

We study the self-forces acting on static scalar and electric test charges in the spacetime of a Schwarzschild black hole. The analysis is based on a direct, local calculation of the self-forces via mode decomposition and on two independent regularization procedures: a spatially extended particle model method and on a mode-sum regularization prescription. In all cases we find excellent agreemen...

3Departamento de Patología, Instituto Nacional de Cancerología (INCan), DF, Mexico 4Subdirección de Investigación Clínica, Instituto Nacional de Cancerología (INCan), DF, Mexico *Corresponding author David Cantú de León, MD, PhD Subdirección de Investigación Clínica Instituto Nacional de Cancerología de México, Av. San Fernando #22 Col. Sección XVI, Tlalpan 14080, DF, México Tel. (+52) (55) 56 ...

Todd Soukup Department of Electrical and Computer Engineering University of Colorado Boulder, CO 80309-0425 We describe a recurrent connectionist network, called CONCERT, that uses a set of melodies written in a given style to compose new melodies in that style. CONCERT is an extension of a traditional algorithmic composition technique in which transition tables specify the probability of the n...

Journal: Canadian Journal of Microbiology Manuscript ID cjm-2015-0425.R2 Manuscript Type: Article Date Submitted by the Author: 21-Oct-2015 Complete List of Authors: Hou, Shaoling; Jinan University, School of environment Shu, Wanjiao; Jinan University, School of environment Tan, Shuo; Jinan University, Department of Chemistry Zhao, Ling; Jinan University, School of environment Yin, Pinghe; Jina...

Michael R. Gleeson,* Shui Liu, Robert R. McLeod, and John T. Sheridan UCD School of Electrical, Electronic and Mechanical Engineering, UCD Optoelectronic Research Centre, The SFI-Strategic Research Cluster in Solar Energy Conversion, College of Engineering, Mathematical and Physical Sciences, University College Dublin, Belfield, Dublin 4, Ireland Department of Electrical and Computer Engineerin...