A method for the synthesis of long chain diamines and tetramines starting from natural α-amino acids is reported. Diamines and tetramines were prepared through the Wittig olefination reaction of N-protected amino aldehydes obtained from phenylalanine and lysine. A 1,2,17,18-tetramine was synthesized using (2S)-1-azido-2-[bis(tertbutoxycarbonyl)-amino]-5-oxopentane as key-intermediate compound.

0020-1693/$ see front matter 2011 Elsevier B.V. A doi:10.1016/j.ica.2011.07.031 ⇑ Corresponding author. Tel.: +39 49 8275172; fax: E-mail address: [email protected] (D. Mo The polymeric [PdCl(dithiocarbamate)]n complexes, in which the ligand ion is dimethyldithiocarbamate (DMDT), pyrrolidine dithiocarbamate (PyDT, (CH2)4NCS2 ) and sarcosine ethyl ester dithiocarbamate (ESDT, EtO2CCH2N(CH...

1. The induction of ornithine decarboxylase activity in mouse 3T3 fibroblasts or an SV-40 transformed 3T3 cell line by serum was prevented by addition of the naturally occurring polyamines putrescine (butane-1,4-diamine) and spermidine. Much higher concentrations of these amines were required to fully suppress ornithine decarboxylase activity in the transformed SV-3T3 cells than in the 3T3 fibr...

The synthesis of 1,4-diamines containing the (Z)-1,4-diaminobut-2-ene subunit via a temporary phosphorus tether/RCM strategy is described. We have developed a new method utilizing phosphorus nuclei as suitable temporary tethers for the coupling of nonracemic allylic amines. This approach allows for the generation of C(2)-symmetric and unsymmetric 1,4-diamines 1-3, which may have considerable sy...

an efficient synthesis of trialkyl (e)-3-(3-oxo-2-3,4-dihydro-2-(1h)-quinoxalinylidene)-prop-1-ene-1,2,3-tricarboxylate derivatives via a simple three-component reaction between benzene-1,2-diamines with dialkyl acetylenedicarboxylates in the presence of k2co3-peg catalytic system at 100 oc was reported. the desired products were obtained in excellent yields (88-92%). various benzene-1,2-diamin...

1-Iodonaphthalene-2,4-diamines in trifluoroacetic acid/chloroform give stable Wheland-like tetrahedral cationic species observable by NMR, through an initial intramolecular protonation. Dynamic equilibria allow proton-deuterium exchange of aromatic protons and provide a mechanism for deiodination of 1-iodonaphthalene-2,4-diamines.

La(OAc)3 has been used as an efficient catalytic system for the synthesis of quinoxalines. This method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for five cycles with consistent activity.

We have synthesized and tested a new binolaldehyde compound 1, against five diamine compounds. Using H NMR (400 MHz) spectroscopy, stable diasteriomeric imine complexes between 1 and five diamines were formed. Chemical shift nonequivalences (up to 0.058 ppm) were obtained for imines. Linear calibration plot was obtained for determining the enantiopurity of diamines.

ECL of several amines containing different numbers of hydroxyl and amino groups was investigated. N-butyldiethanolamine is found to be more effective than 2-(dibutylamino)ethanol at gold and platinum electrodes, and is the most effective coreactant reported until now. Surprisingly, ECL intensities of monoamines, such as 2-(dibutylamino)ethanol and N-butyldiethanolamine, are much stronger than t...

A novel AIE poly(phosphoramidate) was synthesized through an ester ammonolysis reaction by using triethyl phosphate and diamines. Surprisingly, the obtained polymer is sensitive to Cu 2+ can be used as in situ visual detection agent for .