The present study was undertaken to investigate the beneficial effects of widely-prescribed lipid lowering drugs, pitavastatin, atorvastatin and simvastatin 3-hydroxy-3-methylglutaryl-coenzyme-A (HMG-CoA) reductase inhibitors in cognitive dysfunctions of mice. Intra-cerebroventricular (ICV)-Streptozocin-(STZ)- and high-fat diet (HFD)-induced amnesia served as interoceptive memory models where a...

the present study was undertaken to investigate the beneficial effects of widely-prescribed lipid lowering drugs, pitavastatin, atorvastatin and simvastatin 3-hydroxy-3-methylglutaryl-coenzyme-a (hmg-coa) reductase inhibitors in cognitive dysfunctions of mice. intra-cerebroventricular (icv)-streptozocin-(stz)- and high-fat diet (hfd)-induced amnesia served as interoceptive memory models where a...

In rats, the pharmacological (interoceptive) effects of 0.4 mg/kg nicotine can serve as a conditional stimulus in a Pavlovian conditioning task. Nicotine administration is paired with intermittent access to a liquid sucrose unconditional stimulus; sucrose is withheld on saline sessions. An increase in sucrose receptacle entries (goal tracking) on nicotine sessions indicates conditioning. Rats w...

DNA of human papillomavirus type 18 is present in several human cancer cell lines that were derived from oral or cervical tumors, and it is known that several features of the transformed phenotype can be inhibited by expression of antisense RNA to human papillomavirus (HPV). The present study was performed to find out whether antisense oligonucleotides were also inhibitory. Synthetic Oligonucle...

Primiparous and multiparous sows received a single dietary supplement of either L-tyrosine, L-phenylalanine, or L-glutamate in their feed on the day after weaning and effects on various reproductive traits were evaluated in three experiments. In Exp. 1 and 2, sows received either 0 (control; n = 22 and 64, respectively) or 100 mg of L-tyrosine/kg BW (n = 24 and 62, respectively) on the day afte...

The present work gives a detailed study of in vitro shoot organogenesis of the ornamental onion A. altissimum Regel from the buds of the middle layer of the inflorescences. The course of morphogenesis was examined by light and scanning electron microscopy. Histological observation revealed that during 3 5 days of culture on the BDS medium supplemented with 2.0 mg∙L−1 of BA and 2.0 mg∙L1 of NAA ...

Fresh asparagus (Asparagus officinalis L.) deteriorates rapidly after harvest. Early enzymatic changes that follow harvesting of asparagus are important factors contributing to postharvest deterioration. We held asparagus spears at 25°C for up to 5 days after harvest and examined changes in the activities of Acid invertase (AI), Sucrose Synthase (SS), Glutamine Synthetase (GS) and Phenylalanine...

The aim of this study was to adjust the basic culture medium for germination pollen grains different species from genus Hylocereus. Pollen Hylocereus polyrhizus Weber and undatus (Haw.) Britton & Rose were withdrawn anthers flowers bagged previous day, before its opening. Then, with a brush, spread on surface Petri dishes containing 20 mL medium. Four experiments sequentially installed, conside...

————————————— DOSAGE AND ADMINISTRATION ————————————— • Administer oxaliplatin in combination with 5-fluorouracil/leucovorin every 2 weeks. (2.1): – Day 1: Oxaliplatin 85 mg/m intravenous infusion in 250–500 mL 5% Dextrose Injection, USP and leucovorin 200 mg/m intravenous infusion in 5% Dextrose Injection, USP both given over 120 minutes at the same time in separate bags using a Y-line, follow...

BACKGROUND/AIMS In our previous studies, rats on insulin treatment (5 U/day) and oral glucose to avoid hypoglycemia had reduced neointimal growth after arterial injury. However, plasma glucose in the insulin-treated rats was lower than normal and the effect of oral glucose remained undetermined. In this study, the effects of normoglycemic hyperinsulinemia and oral glucose or sucrose were invest...