An efficient synthesis of the 1,l'-dihydroxy-2,2'-(thiodimethy1ene)bis-9(10H)- anthrone (5) is described. Reaction of 1 -methoxy-2-(bromomethy1)-9,lOanthraquinone (1) with excess sodium sulfide in ethanol, demethylation to the corresponding hydroxy and subsequent selective reduction produced the title compound in high yield.

An efficient synthesis of the 1-hydroxy-2-(prop-2'-enyl)9-anthrone is described. Selective nitration of anthraquinone, reduction to the corresponding amine, diazotization and treatment by sulfuric acid solution afforded the 1-hydroxy-9,10-anthraquinone in good yield as the key intermediate. Reaction with allyl bromide/K2CO3 and subsequent selective reduction accompanie...

an efficient synthesis of the 1,l'-dihydroxy-2,2'-(thiodimethy1ene)bis-9(10h)- anthrone (5) is described. reaction of 1 -methoxy-2-(bromomethy1)-9,loanthraquinone (1) with excess sodium sulfide in ethanol, demethylation to the corresponding hydroxy and subsequent selective reduction produced the title compound in high yield.

In this research, the synthesis of 1,3,5,7-tetrahydroxy-9,10-anthraquinone (1) and two anthrone derivatives, 1,3,5,7-tetrahydroxy-10H-anthracene-9-one (2) 1-hydroxy-3,5,7,9-tetramethoxyanthracene (3) has been done. Compound 1 was synthesized by a symmetrical condensation reaction 3,5-dihydroxybenzoic acid in concentrated sulfuric acid. Reduction carbonyl group compound with SnCl2/HCl-HOAc affor...

Anthralin and some of its derivatives have implied antipsoriatic effect in clinical and pharmaceutical studies. Anthralin is synthesized by different strategies. In this work we report the synthesis of "OEHA" as a precursor of another biological active compound.

Five new 1-hydroxy-2-(1-alkyloxymethyl)-9,10-Anthraquinones (9a-e) have been prepared. Selective nitration of 2-methyl-9,10-anthraquinone, reduction to the corresponding amine, diazotization and treatment by sulfuric acid solution afforded the 1-hydroxy-2-methyl-9,10-anthraquinone in good yield as the key intermediate. Reaction with dimethylsulphate/K2CO3 and subsequen...