[Purpose] This study investigated the flexion-relaxation phenomenon of the erector spinae in elderly women with chronic knee osteoarthritis and determined whether the flexion-relaxation phenomenon can be used as a pain evaluation tool in such cases. [Subjects and Methods] Seventeen elderly females with chronic knee osteoarthritis and 13 healthy young females voluntarily participated in this stu...

Total hip arthroplasty is a common and important treatment for osteoarthritis patients. Long-term cardiovascular effects elicited by osteoarthritis or the implant itself remain unknown. The purpose of the present study was to determine if there is an increased risk of late cardiovascular mortality and morbidity after total hip arthroplasty surgery.A nationwide matched cohort study with data on ...

Inflammation of cartilage is a primary symptom for knee-joint osteoarthritis. Matrix metalloproteinases (MMPs) are known to play an important role in the articular cartilage destruction related to osteoarthritis. Naringenin is a plant-derived flavonoid known for its anti-inflammatory properties. We studied the effect of naringenin on the transcriptional expression, secretion and enzymatic activ...

PURPOSE The goal of this study was to identify baseline prognostic factors of outcome in ankle osteoarthritis patients after intra-articular hyaluronic acid injection. MATERIALS AND METHODS Patients with ankle osteoarthritis who received hyaluronic acid injection therapy were retrospectively reviewed. Each patient received weekly intra-articular hyaluronic acid injections (2 mL) for 3 weeks. ...

The purpose of this study was to investigate the short-term of Theracurmin dose and exercise type on pain, walking ability, and muscle function in patients with knee osteoarthritis. Twenty-five patients with knee osteoarthritis randomly selected to Theracurmin intake (T) group and Theracurmin in combined with exercise (T+E) group. T group (n= 13) was taken orally a capsule of 700 mg, 3 times pe...

The lectin-like, oxidized low-density lipoprotein (ox-LDL) receptor-1 (LOX-1)/ox-LDL system contributes to atherosclerosis and may be involved in cartilage degeneration. The purpose of this study was to determine whether the LOX-1/ox-LDL system contributes to age-related osteoarthritis (OA) in vivo, using LOX-1 knockout (LOX-1 KO) mice. Knee cartilage from 6, 12, and 18-month old (n = 10/group)...

Background Osteoarthritis (OA) is the most common degenerative joint disease [1]. Knee OA an insidious related to structural changes in over many years. Duloxetine, a selective serotonin, and norepinephrine reuptake inhibitor, seems be effective treating neuropathic chronic pain conditions [6]. Objectives The objective of this study was assess efficacy duloxetine tablet compared nonsteroidal an...

background: the sternoclavicular joint (scj) is the only synovial articulation between the upper extremity and the trunk. this joint is one of the most frequently used joints, so osteoarthritis (oa) should be very common. however, there are few studies about oa in this joint.   methods: in this study, 48 sternoclavicular joints from the left and right joints of 23 cases and two left joints from...

Background: Osteoarthritis is a common chronic disease of the musculoskeletal system in older adults. Aim: This study aimed to compare the effects of in-person and distance exercise training on the outcomes of knee injury and osteoarthritis among the elderly with limited literacy. Method: In this two-group randomized clinical trial with a pretest-posttest design, 60 elderly patients with knee i...