PURPOSE We aimed to evaluate the role of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) involving care-dose unenhanced CT to detect extranodal involvement in patients with non-Hodgkin and Hodgkin lymphoma. MATERIALS AND METHODS Lymphoma patients (35 Hodgkin lymphoma, 75 non-Hodgkin lymphoma) who were referred for 18F-FDG PET-CT imaging, follow...

UNLABELLED 18F-FDG kinetics are primarily dependent on the expression of genes associated with glucose transporters and hexokinases but may be modulated by other genes. The dependency of 18F-FDG kinetics on angiogenesis-related gene expression was evaluated in this study. METHODS Patients with primary colorectal tumors (n = 25) were examined with PET and 18F-FDG within 2 days before surgery. ...

PURPOSE 18F-FDG PET/CT is widely used to evaluate indeterminate pulmonary nodules (IPNs). False positive results occur, especially from active granulomatous nodules. A PET-based imaging agent with superior specificity to 18F-FDG for IPNs, is badly needed, especially in areas of endemic granulomatous nodules. Somatostatin receptors (SSTR) are expressed in many malignant cells including small cel...

UNLABELLED Small-animal PET provides the opportunity to image brain activation during behavioral tasks in animal models of human conditions. The present studies aimed to simplify behavioral imaging procedures without a loss of quantitation by using an intraperitoneal route of administration (no cannulation, no anesthesia) and using a standardized uptake value (SUV) to reduce scan duration. ME...

UNLABELLED Multi-detector computed tomography (MDCT) is most commonly used for staging of non-small cell lung cancer (NSCLC). In recent years, 18F- fluorodeoxyglucose positron emission tomography combined with computed tomography (18F-FDG PET/CT) has also been used for the same purpose. Since studies comparing these two methods are scarce, our aim was to determine how the TNM classification and...

AIM To assess the relationship using multimodality imaging between intermediary citrate/choline metabolism as seen on proton magnetic resonance spectroscopic imaging (1H-MRSI) and glycolysis as observed on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in prostate cancer (PCa) patients. METHODS The study included 22 patients with local PCa who were re...

UNLABELLED The purpose of this study was to retrospectively investigate the feasibility of 11C-choline PET, compared with 18F-FDG PET, for the detection of hepatocellular carcinoma (HCC). METHODS A total of 16 HCC lesions in 12 patients were examined with both 11C-choline PET and 18F-FDG PET. Tumor lesions were identified as areas of focally increased uptake, exceeding that of surrounding non...

We read with interest the article by Rosario et al., which summarized practical applicability of accessible imaging method in management thyroid nodules indeterminate cytologically (TNIC) (Rosario, al. 2021). For 18F-FDG-PET, it was stated that a nodule characterized low or absent 18F-FDG uptake is considered at very risk malignance, and thyroidectomy can be excluded if these tests suggest beni...

A 44-year-old female patient presented symptoms and laboratory data consistent with a Cushing’s syndrome. Endocrine investigations and negative pituitary imaging were suggestive of ectopic ACTH secretion. Therefore, the patient underwent fluorine18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and somatostatin receptor scintigraphy (SRS) searching for the ...

Stanford University, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, USA Here we prospectively compared the combined 18F NaF/18F FDG PET/ MRI against 99mTc-MDP in patients with breast and prostate cancers. Twelve patients referred for 99mTc-MDP bone scans were prospectively enrolled from Oct 14 Jan 15. The cohort included 6 men with prostate cancer and 6 women with ...