Background: Psoriasis ( P ) may be complicated by psoriatic arthritis (psoriatic arthropathy PsA ), in 15 % of patients [1]. The risk mortality is increased outpatients compared to the general population [2]. Objectives: aim this study was determine or associated diseases an in-patient autopsy population. Methods: At National Institute Rheumatology 11860 died between 1968 and 1998; among them 1...

Previous studies have revealed that the glucoincretin hormone glucagon-like peptide-1 (GLP-1)(7-36)amide is metabolized by dipeptidyl peptidase-IV (DPP-IV) and neutral endopeptidase 24.11 (NEP) to yield GLP-1(9-36)amide and GLP-1(28-36)amide, respectively, as the principal metabolites. Contrary to the previous notion that GLP-1(7-36)amide metabolites are pharmacologically inactive, recent studi...

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): Scripps Health Krueger Wyeth Grant Background ACS results from unstable atherosclerotic plaques. Current measures to assess risk do not consider the patient’s coronary composition. This was a case control study using prospective single-center registry patients undergoing CCTA (N=2,700) 2017–2020 assoc...

The knowledge of HIV-1 drug resistance continues to increase at an exponential rate. This is particularly true for resistance to HIV-1 protease inhibitors, for which the first resistant variants were described less than two years ago (Otto et al., PNAS 90:7453–7457, 1993). Now resistance to virtually all classes of protease inhibitors has been documented. To keep our readership informed of newl...

OBJECTIVES/HYPOTHESIS Bell's palsy is highly associated with diabetes mellitus (DM). Either the reactivation of herpes simplex virus type 1 (HSV-1) or diabetic mononeuropathy has been proposed to cause the facial paralysis observed in DM patients. However, distinguishing whether the facial palsy is caused by herpetic neuritis or diabetic mononeuropathy is difficult. We previously reported that ...

There is a large number of patients with chronic kidney disease (CKD), diabetes mellitus (DM), and hypertension (HT) but whether the targets on blood pressure (BP) control in patients with DM and/or CKD are met is not clear. This narrative review therefore investigated evidence on services aimed at achieving desirable clinical results in patients with CKD and DM, and HT in Australia. Literature...

We recently discovered a method whereby proline-requiring (pro) mutants of some strains of Escherichia coli K-12 can be selected at high frequency (Table 1). The method seems to involve the general principle of differential growth rates. Only pro E. coli K-12 mutant strains grew in Penassay Broth (Difco) containing 1 to 3 ,ug/ml of 4-nitropyridine-N-oxide (4NPO), 10 ,ug/ml of 4-nitrosopyridine-...