Hantaviruses cause two diseases with prominent vascular permeability defects, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. All hantaviruses infect human endothelial cells, although it is unclear what differentiates pathogenic from nonpathogenic hantaviruses. We observed dramatic differences in interferon-specific transcriptional responses between pathogenic and nonpa...

Background: This study was aimed to observe the relationship of serum cholesterol with incidence of ovarian tumours (benign and malignant) in pre and postmenopausal Pakistani women. Effect of type (benign and malignant) and state of disease (FIGO stages of malignant tumours) on serum was also the objective of the study. Methods: Thirty-five clinically and histopathologically confirmed patients ...

It will be shown that extended Krylov subspaces –under some assumptions– can be retrieved without any explicit inversion or system solves involved. Instead we do the necessary computations of A−1v in an implicit way using the information from an enlarged standard Krylov subspace. It is well-known that both for classical and extended Krylov spaces, direct unitary similarity transformations exist...

This paper proposes an evolutionary approach to Bandgap Voltage Reference (BVR) design. The efficiency and feasibility of this method for solving the circuit design task are investigated. For demonstration purpose, two sub-1V BVR circuits are chosen. Circuit optimization is performed for various algorithm options. We have compared the design results obtained for purely random and deterministic ...

In this study, we developed a gas chromatography-mass spectrometry (GC-MS)-based serum metabolomic analysis method to evaluate the effects of pirfenidone in rats with acute paraquat poisoning. The rats were divided into four groups, acute paraquat poisoning group, low pirfenidone group, high pirfenidone group, and control group. The acute paraquat poisoning group rats were given 20 mg/kg of par...

Trends in completed suicide by method were analysed for Belgium between 1968-1972 and 1978-1981, using the information reported on death certificates. Around 1980, hanging was the most preferred method of suicide in both sexes, followed by firearms in males and poisoning by solid and liquid substances in females. Between 1970 and 1980, rates for all but one method (domestic gas) increased. The ...

BACKGROUND The rate of non-fatal self-poisoning in Sri Lanka has increased in recent years, with associated morbidity and economic cost to the country. This review examines the published literature for the characteristics and factors associated with non-fatal self-poisoning in Sri Lanka. METHODS Electronic searches were conducted in Psychinfo, Proquest, Medline and Cochrane databases from inc...

Hantaviruses cause two human diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantaviruses infect human endothelial cells but cause little or no damage to the infected endothelium. We analyzed with Affymetrix DNA Arrays (Santa Clara, CA) the endothelial cell transcriptional responses directed by hantaviruses associated with HPS [New York-1 virus (N...