The possibility of imparting an antibacterial effect to cellulose tissue dyed with the product azo coupling diazotized 4,4’-diaminostilbene-2,2’-disulfonic acid 8-hydroxyquinoline has been shown. It was found that fabrics by fixing dye a silver salt have significant effect, which lasts at least 10 washings.

The hepatocyte growth factor receptor (HGFR or c-Met) is a driver of multiple cancer subtypes. While there are several c-Met inhibitors in development, few have been approved for clinical use, warranting the need for continued research and development of c-Met targeting therapeutic modalities. The research presented here demonstrates a particular class of compounds known as isothiocyanatostilbe...

216 words Introduction: 750 words Discussion: 1391 words Non-standard abbreviations: mAChR, muscarinic cholinergic receptor; DIDS, 4,4’ diisothiocyanatostilbene-2,2’-disulfonic acid; NPPB, 5-nitro-2-(3-phenylpropylamino) benzoic acid; Oxo-M, oxotremorine-M; DMEM, Dulbecco’s modified Eagle’s medium; 4DAMP, 4-diphenylacetoxy-N-methylpiperidine methiodide; AF-DX 116, 11-[[2[(diethylamino)methyl]-1...

The role of isothiocyanate (ITC) in blocking epithelial restitution after injury and in the recovery of round wounds was examined in the ex vivo guinea pig stomach and in rat gastric mucosal-1 (RGM1) cells, respectively. For this, recovery of transepithelial electrical resistance and morphology after injury or the closure of round wounds was evaluated in the presence of 4,4'-diisothiocyanatosti...

Ionic liquid 1,3-disulfonic acid imidazolium trifluoroacetate ([Dsim][TFA]) has been exploited as a highly efficient catalyst for the one-pot pseudo five-component reaction of phenylhydrazine (2 eq.) with ethyl acetoacetate (2 eq.) and arylaldehydes (1 eq.) in ethanol (reflux conditions). In this reaction, 4,4′‐(arylmethylene)‐bis(3‐methyl‐1‐phenyl‐1H‐ pyrazol‐5‐ol)s have been obtained in high ...

Anion channels are thought to participate in signal transduction and turgor regulation in higher plant cells. The regulation of hypocotyl cell elongation is a situation in which these channels could play important roles because it involves ionic fluxes that are implicated in turgor control and orchestrated by various signals. We have used a pharmacological approach to reveal the contribution of...

With the use of an alkaliphilic bacterium, Corynebacterium humireducens MFC-5, this study investigated the reduction of goethite (α-FeOOH) and degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) mediated by different humic substances (humics) and quinones in alkaline conditions (pH of 9.0). The results indicated that (i) using sucrose as the electron donor, the strain MFC-5 was capable of red...