In order to reduce background noise in noisy speech, we have investigated a noise reduction method based on a noise reconstruction system (NRS) with an adaptive line enhancer (ALE). The NRS uses a noise reconstruction filter (NRF) estimating the background noise. In case a fixed step size for updating tap coefficients of the NRF is used, it is difficult to estimate the background noise accurate...

An assessment of the nitrogen fertilization efficiency should not only include quantitativeand qualitative yield changes, but also an analysis of formation some indicators such as: Nharvest index (NHI), N use efficiency (NUE), N utilization efficiency (NUtE), N agronomicefficiency (NAE), N physiological efficiency (NPE) and N apparent recovery fraction (NRF).The objective of the study was the e...

Contractile activity induces mitochondrial biogenesis and increases glucose transport capacity in muscle. There has been much research on the mechanisms responsible for these adaptations. The present paper reviews the evidence, which indicates that the decrease in the levels of high-energy phosphates, leading to activation of AMP kinase (AMPK), and the increase in cytosolic Ca(2+), which activa...

There is considerable interest in the use of drugs and other methods for protecting implanted neural stem cells (NSCs) from the adverse environment of injured tissue for successful cell therapy. Resveratrol can modify cardiac stem cells to enhance their survival and differentiation, however, its effect and the mechanism underlying its neuroprotective effect on NSCs following stroke remain to be...

BACKGROUND Light chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There is no treatment to reverse LC tissue toxicity. We tested the hypothesis that nanoliposomes composed of monosialoganglioside, phosphatidylcholine, ...

BACKGROUND Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatitis and fibrosis. Heme oxygenase-1 (HO-1), an important antioxidant enzyme catalyzing the rate-limiting step in heme degradation, protects against oxidative stress, inflammation,...