introduction: this report describes the synthesis of 2-amino-2-deoxy(s-benzoylthioacetyl)-d-glucose (s-bz-ta-dg), radiolabeled with [99mtc(co)3(oh2)3]+ complex with a procedure including deprotection of the benzoyl group, characterization by hplc using a c18 reverse phase column and preliminary biodistribution study in normal mice. methods: [99mtc(co)3(h2o)3]+ complex was used to label ta-dg w...

  Introduction: This report describes the synthesis of 2-Amino-2-deoxy(S-benzoylthioacetyl)-D-glucose (S-Bz-TA-DG), radiolabeled with [99mTc(CO)3(OH2)3]+ complex with a procedure including deprotection of the benzoyl group, characterization by HPLC using a C18 reverse phase column and preliminary biodistribution study in normal ...

1,1,2-trimethyl-1H-benzo[e]indole is an important heterocyclic compound, its available in reasonable price and can easily modified to make a good intermediate for other derivatives. That quite enough reasons use as starting material new series of compounds with biomolecules such monosaccharides after simple modification. The target molecules show biological activity. So, the current work aiming...

Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [99mTc(H2O)3(CO)3]+ complex. [99mTc]-ECB-DG and [99mTc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na99mTcO4 in 1 mL saline. Radi...

Two deoxyglucose (DG) derivatives, (α,β)-2-deoxy-2-amino(ethylcarbamate)-D-glucose (ECB-DG) and (α,β)-2-deoxy-2-amino(1,2-dihydroxypropyl)-D-glucose (DHP-DG), were synthesized and radiolabeled successfully with [99mTc(H2O)3(CO)3]+ complex. [99mTc]-ECB-DG and [99mTc]-DHP-DG complexes were prepared (96% and 93% radiochemical purities respectively) by using 46 mCi of Na99mTcO4 in 1 mL saline. Radi...