Author(s): Gene E. Robinson, Jody A. Banks, Dianna K. Padilla, Warren W. Burggren, C. Sarah Cohen, Charles F. Delwiche, Vicki Funk, Hopi E. Hoekstra, Erich D. Jarvis, Loretta Johnson, Mark Q. Martindale, Carlos Martinez Del Rio, Monica Medina, David E. Salt, Saurabh Sinha, Chelsea Specht, Kevin Strange, Joan E. Strassmann, Billie J. Swalla and Lars Tomanek Source: BioScience, 60(11):923-930. 20...

OBJECTIVE The purpose of the study was to report our early outcome in the management of multiligament knee injuries with the ligament advanced reinforcement system (LARS). SUBJECTS AND METHODS Between 2007 and 2010, 9 of 11 patients operated on for multiligament knee injuries were included in this study; 2 patients were excluded due to complicated neurovascular injuries, open knee dislocation...

BACKGROUND Injury to the anterior cruciate ligament (ACL) of the knee is common. Following complete rupture of the ACL, insufficient re-vascularization of the ligament prevents it from healing completely, creating a need for reconstruction. A variety of grafts are available for use in ACL reconstruction surgery, including synthetic grafts. Over the last two decades new types of synthetic ligame...

Low anterior resection syndrome (LARS) is increasingly recognized as a concern after low anterior resection for the treatment of rectal cancer. The lack of a precise definition outlining the symptoms and the time course that constitute LARS hinders ongoing research into the incidence, risk factors, pathophysiology, and treatment of this syndrome. This review will outline the current characteriz...

BACKGROUND We investigated very long-term bowel function after total mesorectal excision (TME) with or without preoperative short-course radiotherapy (PRT) for rectal cancer, the risk factors for bowel dysfunction, and the association of bowel dysfunction with health-related quality of life (HRQL). PATIENTS AND METHODS In the TME trial (1996-1999), 1530 Dutch patients with rectal cancer were ...

Objective: The aim of this study was to develop and validate a scoring system for bowel dysfunction after low anterior resection (LAR) for rectal cancer, on the basis of symptoms and impact on quality of life (QoL). Background: LAR for rectal cancer often results in severe bowel dysfunction (LAR syndrome [LARS]) with incontinence, urgency, and frequent bowel movements. Several studies have inve...

CONTEXT Computed tomography coronary angiography (CTCA) has become a common diagnostic test, yet there are little data on its associated cancer risk. The recent Biological Effects of Ionizing Radiation (BEIR) VII Phase 2 report provides a framework for estimating lifetime attributable risk (LAR) of cancer incidence associated with radiation exposure from a CTCA study, using the most current dat...