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زمینه و هدف: مسیر سیگنال دهی wnt نقش مهمی در فولیکولوژنز تخمدان جوندگان ایفا می کند. ولی نقش آن در رویدادهای آپوپتوتیک تخمدان تاکنون مورد بررسی قرار نگرفته است. نظر به اهمیت آپوپتوز در هموستاز و عملکرد بیولوژیک تخمدان، در این مطالعه به بررسی دخالت سیگنال دهی wnt/ßcatenin در توقف رشد فولیکولی و آپوپتوز در مدل pco موش بزرگ آزمایشگاهی (رت) پرداخته شده است.روش بررسی: القا pco در رت های ماده نابالغ ...
This article proposes to study the first 12 years of the Minas Gerais Radium Institute, founded in 1922. Its work in the fight against cancer in Brazil, albeit still little known, is coming to light as its institutional documents are studied. A database has been prepared using information from its patient register, based on which statistical analyses have been done to identify the types of canc...
We evaluated the antimicrobial activities of a cationic Gemini surfactant, trans-1,4-bis[2-(alkanoyloxy)ethyldimethylammonio]-2-butene dichloride [II-m-2(t-butene)] and its derivatives against Gram-positive and Gram-negative microorganisms. The II-m-2(t-butene) compound was previously shown to have good surface activity and biodegradability. A dodecanoyloxy derivative (m = 12) of II-m-2(t-buten...
FPGA implementation projects will use a Terasic DE2i-150 development board, as shown below. The DE2i-150 features an Intel Atom N2600 processor and an Altera Cyclone IV GX FPGA, along with a variety of standard I/O peripherals (USB, Ethernet, VGA, etc.). The DE2i-150 ships with Yocto Linux pre-installed. My recommendation is to stick with Yocto, rather than installing a more mainstream distribu...
It has been reported that many women referred to outpatient colposcopy clinics fail to attend for their appointments. The aim of this paper is to search the literature to assess the extent of default from colposcopy and to identify interventions, suitable for implementation within primary care, to reduce the proportion of women defaulting. Searches were performed on MEDLINE, PsychLIT, Bids and ...
Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation.
OBJECTIVES MicroRNAs, a class of noncoding RNAs, play roles in human diseases. MicroRNA-223 (miR-223) is reported to play critical roles in osteoclastogenesis. The purpose of this study was to analyze the expression pattern of miR-223 in rheumatoid arthritis (RA) synovium and examine the suppression of osteoclastogenesis from human peripheral blood mononuclear cells (PBMC) by overexpression of ...
The title compound, C(8)H(18)N(4)O(2) (2+)·2Cl(-), contains two oxime groups. The methyl oxime group has a Z configuration, and the ethyl oxime group is disordered, with both Z and E configurations in occupancies of 0.840 (8) and 0.160 (8), respectively. In the crystal structure, there are a number of N-H⋯Cl hydrogen bonds.
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