The stem-cell leukemia (SCL, also known as TAL1) gene encodes a basic helix-loop-helix transcription factor that is essential for the initiation of primitive and definitive hematopoiesis, erythrocyte and megakarocyte differentiation, angiogenesis, and astrocyte development. Here we report that the zebrafish produces, through an alternative promoter site, a novel truncated scl (tal1) isoform, sc...

About 50% of patients with the polymyositis/scleroderma (PM-Scl) overlap syndrome are reported to have autoantibodies to a nuclear/nucleolar particle termed PM-Scl. The particle is composed of several polypeptides of which two have been identified as autoantigens. In this report, human cDNA clone coding for the entire 75-kD autoantigen of the PM-Scl particle (PM-Scl 75) was isolated from a MOLT...

Spindle-cell lipoma (SCL) is a variant of lipoma, usually presenting in the neck or trunk. SCL of the oral cavity is rare. Some cases of oral SCL have been reported; however, the clinico-pathologic characteristics of oral SCL are still unknown. Here we report on 2 cases and review 33 cases of oral SCL published in the literature. The patients were 23 men and 12 women, with a mean age of 55 year...

The importance of the electron loss from the separate confinement layer (SCL) to the p-cladding in 1.5 μm lasers is analysed comparing two structures. One is a regular structure with strained InGaAsP quantum wells and a 1.15 μm emitting InGaAsP SCL and the second one incorporates an additional In0.81Ga0.19P electron stopper layer (about 50 meV high) at the interface between the p-cladding and t...

The Symptom Checklist - Post-Traumatic Stress Disorder Scale (SCL-PTSD), also known as Crime-Related PTSD Scale has been validated in survivors of interpersonal trauma in the general population. However, the psychometric properties have not been investigated in a clinical setting for patients with PTSD from diverse traumatic events. This study investigates the reliability and validity of the Ko...

Blood and endothelial cells arise in close association in developing embryos, possibly from a shared precursor, the hemangioblast, or as hemogenic endothelium. The transcription factor, Scl/Tal1 (stem cell leukemia protein), is essential for hematopoiesis but thought to be required only for remodeling of endothelium in mouse embryos. By contrast, it has been implicated in hemangioblast formatio...

Polyhydroxyalkanoates (PHAs) composed of a mixture of short-chain-length-medium-chain-length (SCL-MCL) hydroxyacyl monomers are biologically produced polyesters that have properties ranging from thermoplastic to elastomeric, dependent on the molar ratio of SCL to MCL monomers incorporated into the copolymer. Because of the potential wide range of properties and applications for SCL-MCL PHA copo...

Three dimensional particle-in-cell (PIC) simulations are conducted to measure the space charge limited (SCL) currents in coaxial cylindrical diodes. New cut-cell emission and absorption boundary algorithms implemented in the electromagnetic PIC code, VORPAL are utilized for this study. Comparisons of VORPAL SCL current results are made with i) theoretical SCL current results for the one dimensi...

The paper presents an application of Structural Correspondence Learning (SCL) (Blitzer et al., 2006) for domain adaptation of a stochastic attribute-value grammar (SAVG). So far, SCL has been applied successfully in NLP for Part-of-Speech tagging and Sentiment Analysis (Blitzer et al., 2006; Blitzer et al., 2007). An attempt was made in the CoNLL 2007 shared task to apply SCL to non-projective ...

Purpose. To investigate the effect of tear protein deposition on the change in oxygen permeability (Dk) of soft contact lenses (SCL). Methods. Three hydrogel lenses (polymacon, nelfilcon A, and etafilcon A) and two silicon hydrogel lenses (lotrafilcon A and balafilcon A) were investigated. Etafilcon A lenses were incubated in artificial tear solution for 1, 6, 12, and 48 h, whereas the other SC...