نتایج جستجو برای: 4 aminosalicylic acid

تعداد نتایج: 1924350  

Journal: :The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2005
Fatih Tekin Sezgin Vatansever Omer Ozütemiz Ahmet Musoğlu Tankut Ilter

Ascites in the course of Crohn's diseases is rarely seen and usually is a result of a concomitant malignancy, infection or thrombosis of portal or hepatic veins. In this article, a 55-year-old female patient suffering from severe ascites and finally diagnosed as Crohn's disease is presented. Further investigations revealed no malignancy, peritoneal infection or vein thrombosis. Treatment of Cro...

Journal: :Gut 1992
E A Masson J M Rhodes

Nephrotoxicity in association with 5-aminosalicylic acid therapy is well recognised. In this patient the nephrotoxicity only became apparent after severe weight loss had occurred in association with nephrogenic diabetes insipidus. The patient aged 26 with ulcerative colitis received resin coated mesalazine (Asacol) 1200 mg/day and lost 12 kg in weight over a four month period, only complaining ...

Journal: :Journal of pharmaceutical and biomedical analysis 2011
Lan Hong Wendy Jiang Wei Zheng Su Zeng

Para-aminosalicylic acid (PAS), an approved drug for treatment of tuberculosis, is a promising therapeutic agent for treatment of manganese (Mn)-induced parkinsonian syndromes. Lack of a quantifying method, however, has hindered the clinical evaluation of its efficacy and there upon new drug development. This study was aimed at developing a simple and effective method to quantify PAS and its ma...

2009
Yoshimura Shin Kawano Kentaro Matsumura Ryusuke Sugihara Narumi Furuno Koji

N-acetyl 5-aminosalicylic acid (5-AcASA) that was intracellularly formed from 5-aminosalicylic acid (5-ASA) at 200 microM was discharged 5.3, 7.1, and 8.1-fold higher into the apical site than into the basolateral site during 1, 2, and 4-hour incubations, respectively, in Caco-2 cells grown in Transwells. The addition of flavonols (100 microM) such as fisetin and quercetin with 5-ASA remarkably...

Journal: :Gut 1992
A Ireland J D Priddle D P Jewell

Isolated human colonic epithelial cell suspensions were incubated with either 0.1 mM 5-aminosalicylic acid (5-ASA) or 0.1 mM acetylaminosalicylic acid (Ac-ASA) for up to two hours. Intra- and extracellular 5-ASA and Ac-ASA were measured by high performance liquid chromatography. Mean 5-ASA uptake in one hour was 160.5 nmol/g dry weight, compared with an Ac-ASA uptake of only 5.75 nmol/g dry wei...

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