ABBREVIATIONS: μmMicrometer, nmNanometer, PMMA Poly (methylmethacrylate), PACA Poly (alkylcyanoacrylate), PMM Poly (methylidenemalonate), SME Sub-micron emulsion, PAMAM Polyamido amines, 5-ASA 5-Aminosalicylic acid, McMolar mass of the core, MmMolar mass of the branched monomer, MtMolar mass of the terminal groups, ncCore multiplicity, nmBranch-juncture multiplicity, GGeneration number, CMCCrit...

Inflammation of the rat distal intestine was induced by intradermal sensitization and subsequent multiple intrajejunal challenge with the hapten 2,4,6-trinitrobenzenesulphonic acid (TNBS) via an implanted catheter. The time course of the inflammatory reaction was followed by determination of the enteritis score and measurement of in vitro eicosanoid formation of homogenates of the gut after 0, ...

INTRODUCTION Oral formulations of 5-aminosalicylic acid (5-ASA) for treatment of ulcerative colitis have been developed to minimize absorption prior to the drug reaching the colon. In this study, we investigate the release of 5-ASA from available oral mesalamine formulations in physiologically relevant pH conditions. METHODS Release of 5-ASA from 6 mesalamine formulations (APRISO®, Salix Phar...

Para-aminosalicylic acid (PAS), an FDA-approved anti-tuberculosis drug, has been used successfully in the treatment of severe manganese (Mn)-induced Parkinsonism in humans [Jiang Y-M, Mo X-A, Du FQ, Fu X, Zhu X-Y, Gao H-Y, et al. Effective treatment of manganese-induced occupational Parkinsonism with p-aminosalicylic acid: a case of 17-year follow-up study. J Occup Environ Med 2006;48:644-9]. T...

In this work is represented conceptual model of robot-manipulator for capture and 10 holding no-cooperation client spacecraft, which has Payload Adapter interface PAS 1666 S, PAS 11 1194 C, PAS 1666 MVS, PAS 1184 VS, when there are dynamic errors of linear and angular position 12 of client spacecraft in the interval +/-50 per minute and +/-0.1 meters per minute respectively. 13

OBJECTIVE To determine the size of obesity differences associated with educational level in the adult population in Spain. DESIGN Three cross sectional studies representative of the adult population in Spain were carried out in 1987, 1995, and 1997. SETTING The general population in Spain. PARTICIPANTS 11 461 men and 10 219 women aged 25 to 64 years. MAIN RESULTS For both men and women ...

Ulcerative colitis is a chronic disease with recurrent symptoms and significant morbidity. The precise etiology is still unknown. As many as 25 percent of patients with ulcerative colitis have extraintestinal manifestations. The diagnosis is made endoscopically. Tests such as perinuclear antineutrophilic cytoplasmic antibodies and anti-Saccharomyces cerevisiae antibodies are promising, but not ...