نتایج جستجو برای: 4 thiadiazole

تعداد نتایج: 1304406  

Journal: :Metal-Based Drugs 1997
Andrei Jitianu Marc A. llies Fabrizio Briganti Andrea Scozzafava Claudiu T. Supuran

Complexes containing the anions of 5-benzoylamido-1,3,4-thiadiazole-2-sulfonamide and 5-(3-nitro-benzoylamido)-1,3,4-thiadiazole-2-sulfonamid as ligands, and V(IV); Cr(III); Fe(III); Co(II); Ni(II); Cu(II) and Ag(I) were synthesized and characterized by standard procedures (elemental analysis; IR, electronic, and EPR spectroscopy; TG, magnetic and conductimetric measurements). The original sulf...

Journal: :Acta poloniae pharmaceutica 2015
Subhas S Karki Vivek Rana Ramjith U Sivan Sujeet Kumar Vinayakumar Renuka Sureshbabu A Ramareddy Prasanna G Subbarao Sudam C Si

A number of imidazo[2,1-b][1,3,4]thiadiazole derivatives having alkyl and aryl moieties attached to positions 2 and 6 of imidazo[2,1-b][1,3,4]thiadiazole nucleus, respectively, were prepared and characterized by IR, NMR and mass spectroscopy. Antiinflammatory activity was evaluated by carrageenan-induced rat paw edema assay. By 5th hours, all compounds demonstrated anti-inflammatory activity si...

2012
Sung Kwon Kang Nam Sook Cho Siyoung Jang

In the title compound, C(4)H(6)N(2)OS(2), the dihedral angle between the five-membered heterocyclic ring and the plane of the eth-oxy group is 4.9 (2)°. The 1,3,4-thiadiazole-2-thione unit is planar, with an r.m.s. deviation of 0.011 Å from the corresponding squares plane defined by the seven constituent atoms. In the crystal, pairs of N-H⋯S hydrogen bonds link the mol-ecules into inversion dim...

2017
SAID A. EL-FEKY

Several new fluorinated quinazolinone derivatives were prepared and evaluated for in vitro anti-inflammatory activity. The molecular modelling study was performed for compounds 4, 8, 9, 10 and 13. The tested compounds showed strong interactions at the COX-2 binding sites. Compounds 8, 13, 9, and 10 containing triazole, thiadiazole, and oxadiazole rings showed the highest in vitro anti-inflammat...

Journal: :Chemical communications 2008
Xizhe Liu Rui Zhu Yong Zhang Bin Liu Seeram Ramakrishna

Anionic polyfluorene and oligofluorene derivatives were synthesized and utilized as organic dye sensitizers in dye sensitized solar cells to show a maximum power conversion efficiency of 1.39%.

S.D. Srivastava

A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. The synthesised compounds have been screened in vitro for their antimicrobial acti...

Journal: :Acta Crystallographica Section E Structure Reports Online 2010

2017
Sobhi M Gomha Mohamad R Abdelaziz Nabila A Kheder Hassan M Abdel-Aziz Seham Alterary Yahia N Mabkhot

BACKGROUND Many heterocyclic compounds containing thiazole or 1,3,4-thiadiazole ring in their skeletons have been reported to possess various pharmacological activities especially anticancer activities. RESULTS 4-Methyl-2-phenylthiazole-5-carbohydrazide (2) was used as a synthon to prepare 2-(4-methyl-2-phenylthiazole-5-carbonyl)-N-phenylhydrazinecarbothioamide (3) and 2-(2-(4-methyl-2-phenyl...

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