celecoxib is classified as none traditional nonsteroidal anti-inflammatory drugs (nsaids). this compound has conventional properties of nsaids such as anti-inflammatory, analgesic, and antipyretic activities beside reduced risk of gastrointestinal side effect of traditional nsaids such as ibuprofen. this compound gets a second sale rank of nsaids market at 2016 in the world and sales more than ...

Celecoxib is classified as none traditional nonsteroidal anti-inflammatory drugs (NSAIDs). This compound has conventional properties of NSAIDs such as anti-inflammatory, analgesic, and antipyretic activities beside reduced risk of gastrointestinal side effect of traditional NSAIDs such as ibuprofen. This compound gets a second sale rank of NSAIDs market at 2016 in the world and sales more than ...

Celecoxib is classified as none traditional nonsteroidal anti-inflammatory drugs (NSAIDs). This compound has conventional properties of NSAIDs such as anti-inflammatory, analgesic, and antipyretic activities beside reduced risk of gastrointestinal side effect of traditional NSAIDs such as ibuprofen. This compound gets a second sale rank of NSAIDs market at 2016 in the world and sales more than ...

Reaction of 5-sulfosalicylic acid with hydrazine hydrate at pH = 1 results in the formation of the title hydrated salt, 0.5N(2)H(6) (2+)·C(7)H(5)O(6)S(-)·2H(2)O. The hydrazinium dications lie on centres of inversion. They are located between 3-carb-oxy-4-hy-droxy-benzene-sulfonate anions, forming inter-molecular N-H⋯O hydrogen bonds with sulfonate ions and water mol-ecules of crystallisation. F...

The aromatic polyketones 3a-d are versatile compounds for the synthesis of the multi-1,2,3-selenadiazole aromatic derivatives 1a-d. The preparation starts with the reaction between the multi-bromomethylene benzene derivatives 2a-d and 4-hydroxy- acetophenone to give compounds 3a-d which are transformed through the reaction with semicarbazide hydrochloride or ethyl hydrazine carboxylate into the...

In the title sulfonate derivative, C(24)H(26)O(9)S(3), all atoms apart from those of one of the 4-methyl-benzene-sulfonate residues lie approximately in a disc; the dihedral angles between the approximately orthogonal benzene ring and those in the plane are 74.53 (9) and 67.79 (11)°. In the crystal, mol-ecules are consolidated into the three-dimensional architecture by C-H⋯O inter-actions. One ...

The asymmetric unit of the title compound, C(5)H(7)N(2) (+)·C(6)H(6)NO(3)S(-)·C(6)H(7)NO(3)S·H(2)O, contains one 4-ammonio-benzene-sulfonate zwitterion ((+)H(3)NC(6)H(4)SO(3) (-)), one 4-amino-benzene-sulfonate anion (H(2)NC(6)H(4)SO(3) (-)), one 4-amino-pyridinium cation and two half-mol-ecules of water, each lying on a twofold rotation axis. The various ions and molecules in the structure are...

4-(acetoacetamido) arsanilic acid (ii), which was then condensed with aryl aldehydes. the resulting product on reaction with hydrazine hydrate and hydroxyl amine hydrochloride yielded pyrazolines (iv) and isoxazolines (v), respectively. the antimicrobial activity of compounds against a number of microorganisms was evaluated. some of these compounds showed significant antimicrobial activity

The effect of molecular architecture of a surfactant, particularly the attachment position of benzene sulfonate on the hexadecane backbone, at the decane-water interface was investigated using atomistic MD simulations. We consider a series of surfactant isomers in the family of alkyl benzene sulfonates, denoted by m-C16, indicating a benzene sulfonate group attached to the mth carbon in a hexad...