نتایج جستجو برای: 5 (30 m x 0.32 mm

تعداد نتایج: 2538114  

2012
Pavel P. Popov Stephen B. Pope

0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 0.2 0 10 20 30 −10 −5 0 5 10 r (mm) V (m /s ) x/DB = 0.2 0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 0.6 0 10 20 30 −10 −5 0 5 10 r (mm) V (m /s ) x/DB = 0.6 0 10 20 30 −50 0 50 100 150 r (mm) U (m /s ) x/DB = 1.4 0 10 20 30 −10 −5 0 5 10 x/DB = 1.4 r (mm) V (m /s ) Experiment Raman et al. LES/HPDF Liu et al. Merci et al. Fig. 1. Mean ...

Journal: :Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 1993
K Yoshida

The mechanisms of relaxing effect of papaverine on the phenylephrine (10(-6) M)- or the high K+ (30 mM)-induced contracture were studied on the isolated canine corpus cavernosum. Rod shaped preparation of the corpus cavernosum without the tunica albuginea was mounted in a tissue bath, immersed in Tyrode solution and the isometric tension was recorded. Cumulative applications of papaverine (10(-...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010
Wei-Gang Tong Rong Chen William Plunkett David Siegel Rajni Sinha R Donald Harvey Ashraf Z Badros Leslie Popplewell Steven Coutre Judith A Fox Kristi Mahadocon Tianling Chen Peggy Kegley Ute Hoch William G Wierda

PURPOSE SNS-032 is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells. A phase I dose-escalation study of SNS-032 was conducted to evaluate safety, pharmacokinetics, biomarkers of mechanism-based pharmacodynamic (PD) activity, and clinical efficacy. PATIENTS AND ME...

2005
Maurizio C. Capogrossi Takashi Kaku Charles R. Filburn Don J. Pelto Richard G. Hansford Harold A. Spurgeon Edward G. Lakatta

We used left ventricular myocytes from adult rats to investigate the effect of 4f.-phorbol 12-myristate 13-acetate (PMA) and of sn-1,2-dioctanoylglycerol (DiC-8) on the membrane association of protein kinase C (PKC), cytosolic [Ca2], (Cai) homeostasis, and the contractile properties of single cardiac cells. Because PKC activity is known to be highly Ca2+ sensitive, the K+ concentration of the b...

2017
Dominique Unruh

Consider the following symmetric encryption scheme (KG , E,D). KG chooses an AES key. E(k,m) := EAES (k,m)‖032. (032 stands for a string consisting of 32 zeros.) And the decryption D(k, c) does the following: Let c′‖p := c where p has length 32 bit and c′ is all but the last 32 bits of c. m := DAES (k, c′). If p = 032, then D(k, c) returns m. If p 6= 032 and kp = 0 (here kp is the p-th bit of t...

Journal: :Circulation research 1990
M C Capogrossi T Kaku C R Filburn D J Pelto R G Hansford H A Spurgeon E G Lakatta

We used left ventricular myocytes from adult rats to investigate the effect of 4 beta-phorbol 12-myristate 13-acetate (PMA) and of sn-1,2-dioctanoylglycerol (DiC-8) on the membrane association of protein kinase C (PKC), cytosolic [Ca2+], (Cai) homeostasis, and the contractile properties of single cardiac cells. Because PKC activity is known to be highly Ca2+ sensitive, the K+ concentration of t...

Journal: :Japanese journal of pharmacology 1975
T Nasu Y Ishida

Ca sensitivity and energy dependence in the contractile proteins of the glycerinated taenia coli of guinea pig were studied. Above 1 X 10(-7)M Ca caused contraction in muscle which had been immersed in glycerol solution for 7 days in the presence of 5 mM Mg-ATP. Muscles which had been immersed in glycerol for 30 days had a higher Ca sensitivity than ones in glycerol for 7 days. When AMP or ADP ...

Journal: :Indian journal of experimental biology 2005
Dilip K Deka Vellanki Ravi Prakash Santosh K Mishra

In the present investigation we have examined the hypothesis that calcium-dependent K+ channels (K(Ca)) are involved in the sodium nitroprusside (SNP)-induced vasodilatation of goat coronary artery. SNP (10(-9)-3 x 10(-6) M), added cumulatively, relaxed K+ (30 mM)-contracted coronary artery ring segments in a concentration-dependent manner with an EC50 of 1.32 x 10(-7) M (95% CL, 0.93-1.86 x 10...

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