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Patients 627 outpatients (mean age 49 y, 98% men) who had a diagnosis of alcohol dependence according to DSM-IV criteria, who had not drunk for >5 days, but who had a recent history of drinking to intoxication (heavy drinking at least twice during a 1 week period in the 30 days before screening, where heavy drinking was defined as >6 drinks for men and >4 drinks for women). Exclusion criteria i...

To determine the role of endothelin-1 (ET-1) and its receptors in the regulation of calcitonin gene-related peptide (CGRP) release, male Wistar rats were divided into six groups and subjected to the following treatments for 1 wk with or without ABT-627 (an ET(A) receptor antagonist, 5 mg.kg(-1).day(-1) in drinking water) or A-192621 (an ET(B)-receptor antagonist, 30 mg.kg(-1).day(-1) by oral ga...

ARELLANO, C. J., C. S. LAYNE, D. P. O’CONNOR, M. SCOTT-PANDORF, and M. J. KURZ. Does Load Carrying Influence dynamical system analysis to investigate the effect of carrying external loads on the stability of the locomotive system and sagittal plane kinematics. We hypothesized that carrying an additional load at the waist would 1) decrease the dynamic stability of the locomotive system and 2) ca...

Digital microfluidics (DMF), a fluid-handling technique in which picolitre-microlitre droplets are manipulated electrostatically on an array of electrodes, has recently become popular for applications in chemistry and biology. DMF devices are reconfigurable, have no moving parts, and are compatible with conventional high-throughput screening infrastructure (e.g., multiwell plate readers). For t...

Algorithm to Find All Cliques in a Graph A. Ashok Kumar Department of Computer Science , St. Xavier’s College (Autonomous), Palayamkottai 627 002. E-mail: [email protected] S. Athisayanathan Research Department of Mathematics, St. Xavier’s College (Autonomous),Palayamkottai 627 002. E-mail: [email protected] A. Antonysamy Research Department of Mathematics, St. Xavier’s College...

corresponding author: Christoph Börgers, [email protected], phone: 617-627-2366, fax: 617-627-3966 keywords: Hodgkin-Huxley equations, synchronization, type II neurons, gamma oscillations, shunting inhibition

............................................................................................................................................................................... 623 Introduction .......................................................................................................................................................................... 624 Case Study Sites ...............

++Endothelin (ET-1) acts as a potent vasoconstrictor in the human kidney, and this vasoconstriction could contribute to the ischemia seen in acute renal failure. In animal studies, the vasoactive properties of ET-1 are known to be ET(A) receptor-and/or ET(B) receptor-mediated; however, the receptor subtype involved in the human kidney remains to be defined. In a phase I, single-center, double-b...